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Original Article

Commentary: Vitamin C: Antioxidant or Pro-Oxidant In Vivo?

Pages 439-454 | Received 13 Nov 1995, Published online: 07 Jul 2009
 

Abstract

Ascorbic acid has a multiplicity of antioxidant properties, but it can exert pro-oxidant effects in vitro, usually by interaction with transition metal ions. It is as yet uncertain that these pro-oxidant effects have any biological relevance: some of the available data are summarized.

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