99
Views
23
CrossRef citations to date
0
Altmetric
Original Article

Comparative Study of the Abuse Liability of Alprazolam, Lorazepam, Diazepam, Methaqualone, and Placebo

, , , , , & show all
Pages 449-467 | Published online: 03 Jul 2009
 

Abstract

Subjective effects of two benzodiazepines–alprazolam and lorazepam– were compared with two drugs of known abuse potential–diazepam and methaqualone–and placebo. This double-blind, crossover trial tested 30 casual recreational sedative users in a seminaturalistic setting. Methaqualone was more euphoriant and less sedative than the benzodiazepines. Diazepam and lorazepam were more euphoriant than placebo; alprazolam's euphoriant effect did not differ from these treatments. On other measures of abuse liability the benzodiazepines rated similarly, diazepam rating highest.

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.