Nasal Administration of Naloxone Is as Effective as the Intravenous Route in Opiate Addicts

Abstract

Naloxone is used intravenously in opiate addiction in emergency cases, in rapid opiate detoxification, and as a diagnostic tool. This is a study comparing the efficacy of intranasal naloxone to other routes (intravenous/intramuscular) in 17 opiate-dependent patients. The nasal drug administration of naloxone was found to be as effective as the intravenous route. The nasal drug application offers a wide margin of safety for patients and medical staff, especially in emergency situations in regard to infection risks associated with vessel puncture.

Key Words:

• Naloxone
• Opiate addiction
• Nasal administration
• Intravenous application