![Sample our Bioscience journals, sign in here to start your access, Latest two full volumes FREE to you for 14 days]({"type":"image" , "src" : "/sda/5925/TOC-Subject-Sample-2021-Bioscience.jpg"})
Abstract
Background: Periodontitis has been reported to relate closely to systemic diseases. However, a biomarker for periodontal status has not been established.
Methods: A cross-sectional study was conducted using oral and systemic health checkup data of 151 middle-aged men. The serum levels of adiponectin and its subfractions were also analysed.
Results: The ratio of high molecular weight adiponectin to total adiponectin was significantly lower in subjects with periodontal pockets. Moreover, this ratio independently associated with periodontal condition.
Conclusions: The ratio of HMW adiponectin to total adiponectin could be a novel biomarker for evaluation of periodontal health in middle-aged men.
Acknowledgements
The authors thank Ms. Maki Yamashita for her exceptional secretarial assistance.
Declaration of interest
The work was supported by Grants-in-Aid for Scientific Research (Nos. 19592398, 19592420, 21792164) from the Japanese Society for the Promotion of Science, High-Tech Research Center Project for Private Universities: matching fund subsidy from the Ministry of Education, Culture, Science, Sports and Technology (MEXT) (2007–2011), and Osaka Dental University Research Funds (07-05).