Endoluminal full-thickness resection of GI lesions: A new device and technique

Abstract

Full-thickness resection techniques are of growing interest in the field of endoscopic removal of tumors or their precursors in the digestive tract. A new dedicated full-thickness resection device has been developed based on the combination of the OTSC clip, an enlarged resection cap and an integrated snare. The device prototype allows combined resection of all gastrointestinal organ wall layers in one maneuver, up to a size of 3 x 3 cm. The device has been pre-clinically tested to demonstrate feasibility of full-thickness resection in the colon. Two clinical cases have been performed successfully to date.

Key words::

• Endoscopy
• full-thickness resection
• OTSC

Acknowledgements

Basic research on tissue resection techniques that enables the development of the full-thickness resection device was funded by the European Commission within the VECTOR project in the 6^th Framework Program, Information Society Technologies - Contract Number 033970.

Declaration of interest: All authors, except Thomas Kratt, are employees of the company Ovesco Endoscopy AG, Tuebingen, Germany, or have an ownership interest. The costs of pre-clinical experiments have also been covered by Ovesco Endoscopy.