Roux-en-Y gastrojejunal bypass using a hybrid NOTES-12mm trocar technique in a porcine model

Abstract

Aims To evaluate the feasibility and safety of Roux-en-Y gastrojejunal bypass procedure using a hybrid NOTES-12 mm trocar technique in a survival porcine model. Material and methods The procedure was carried out on ten pigs. Two gastroscopes were introduced through the mouth and through a 12 mm trocar, respectively. A mechanical circular gastro-jejunal anastomosis was created by introducing a stapler after the trocar incision was enlarged. A 21 mm EEA OrVil circular stapler was utilized in the first six pigs and a 25 mm one was used in the other four. All pigs were fed beginning 24 hours after the procedure and were euthanized three weeks later. Results The procedure was successfully completed in all ten animals. The mean length of the skin incision was 2.5 cm. All pigs survived without complications. Endoscopic inspection detected anastomotic strictures in 5/6 of the 21 mm-stapler and in 0/4 of the 25 mm-stapler anastomoses ( p < 0.05).

Conclusion Roux-en-Y gastrojejunal bypass using a hybrid NOTES-single 12 mm trocar access technique is a simple and safe procedure in a survival porcine model. Functional results need to be evaluated by further studies.

Keywords:

• Gastrojejunal bypass
• Roux-en-Y
• NOTES

Acknowledgments

The authors are grateful to Linda Inverso Moretti for editing the English version of this manuscript.

Disclosure of interest

Lino Polese, Roberto Luisetto, Andrea Porzionato, Doralba Mastrogiacomo, Raffaele De Caro, Lorenzo Norberto, and Stefano Merigliano have no competing financial interests.