Magnetic resonance imaging control of laser destruction of hepatic metastases: Correlation with post-operative dynamic helical CT

H. R. S. Roberts Department of Imaging, The Middlesex Hospital, University College London Hospitals, London, UK

M. Paley Department of Imaging, The Middlesex Hospital, University College London Hospitals, London, UK

V. R. Sams The Department of Histopathology, University College and Middlesex School of Medicine, London

I. D. Wilkinson Department of Imaging, The Middlesex Hospital, University College London Hospitals, London, UK

W. R. Lees Department of Imaging, The Middlesex Hospital, University College London Hospitals, London, UK

M. A. Hall-craggs Department of Imaging, The Middlesex Hospital, University College London Hospitals, London, UK

S. G. Bown The National Medical Laser Centre, The Rayne Institute, University College and Middlesex School of Medicine, London

show all

Summary

Interstitial laser photocoagulation (ILP) is currently limited by deficient per-procedural monitoring. The purpose of this study was to evaluate MR control of ILP of hepatic metastases. Twenty-two laser activations were used to treat eight metastases in seven patients under local anaesthesia and sedation. Laser energy was delivered via optical fibres positioned in the tumour under ultrasound guidance. T1-weighted FLASH and spin-echo sequences were used to monitor the procedure. Enhanced CT was performed at 24 h to assess thermal necrosis. FLASH imaging showed an enlarging area of signal change during ILP. The final extent of this correlated closely with the extent of tissue necrosis on CT. Spin-echo imaging was disappointing because of poor contrast between the treated tissue and normal liver/untreated tumour. Per-procedural MR imaging accurately and reliably depicts ILP-induced necrosis. MR control may permit more widespread application of ILP to the treatment of hepatic tumours.

Keywords:

Reprints and Corporate Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

To request a reprint or corporate permissions for this article, please click on the relevant link below:

Order Reprints Request Corporate Permissions

Academic Permissions

Please note: Selecting permissions does not provide access to the full text of the article, please see our help page How do I view content?

Obtain permissions instantly via Rightslink by clicking on the button below:

Request Academic Permissions

If you are unable to obtain permissions via Rightslink, please complete and submit this Permissions form. For more information, please visit our Permissions help page.

Magnetic resonance imaging control of laser destruction of hepatic metastases: Correlation with post-operative dynamic helical CT

Information for

Open access

Opportunities

Help and information

Magnetic resonance imaging control of laser destruction of hepatic metastases: Correlation with post-operative dynamic helical CT

Summary

Reprints and Corporate Permissions

Academic Permissions

Related research

To cite this article:

Download citation

Information for

Open access

Opportunities

Help and information

Keep up to date

Your download is now in progress and you may close this window

Login or register to access this feature