Summary
During 1992–95 79 patients suffering from acoustic neuromas were treated by radiosurgery at the Department of Neurosurgery of the University Medical School at Graz. Fifty-one patients underwent γ-knife treatment as primary therapy, 28 patients after neurosurgical operation because of remaining or recurrent tumour. The tumour diameter ranged from 5.3 to 37.7 mm and patient follow-up was 3–6 years. In all patients contrast-enhanced CT (until 1993) or MRI was performed, with the stereotactic head-frame applied to determine the target. The total central tumour dose varied from 14 to 50 Gy, the total peripheral dose ranged from 9 to 18 Gy, respective to the 30–70% isodose. Tumour shrinkage was seen in 10.1% of the neuromas and 57.0% showed variable changes in morphology, due to a partial necrosis. There was no increase in tumour size during the study. The overall hearing preservation rate was approximately 85%. Seven patients became deaf after radiosurgery, six patients (7.6%) developed facial neuropathies after stereotactic treatment and two patients (2.5%) trigeminal symptoms. Three patients developed a post-therapeutic perifocal oedema, two of them asymptomatic, the other one with neurological signs, including vertigo, nausea and dizziness. All patients returned to their preoperative function level within a couple of days. Stereotactic radiosurgery using the Leksell γ-knife is a safe, non-invasive therapy for acoustic neuromas and is a good alternative to microsurgery in cases of inoperable patients and those who refused surgery. For recurrent or partially removed tumours, radiosurgery seems to be the therapy of choice.