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ABSTRACT
Objectives The aim of this study was to investigate serum, stimulated and unstimulated salivary magnesium in postmenopausal women with xerostomia.
Materials A case–control study was carried out on 60 selected postmenopausal women aged 41–77 years with or without xerostomia (30 as cases with xerostomia and 30 as controls without xerostomia), conducted at the Clinic of Oral Medicine, Tehran University of Medical Sciences. Unstimulated and paraffin-stimulated saliva samples were obtained by expectoration. Magnesium concentration was determined by the spectrophotometer method. Statistical analysis was carried out using Student's t-test.
Results The mean serum concentration, but not stimulated and unstimulated whole saliva magnesium concentrations, was significantly higher in the cases than in the controls.
Conclusion Serum magnesium level appears to be associated with xerostomia in menopause.
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Conflict of interest The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this paper.
Source of funding The present study was supported by a grant from Tehran University of Medical Sciences.