New sesquiterpene coumarins from the roots of Ferula flabelliloba

Abstract

Three new sesquiterpene coumarins, namely, farnesiferone B (1), flabellilobin A (2) and flabellilobin B (3), together with nine known compounds, ligupersin A, 7-epi-gamma-eudesmol, persicasulfide A, conferdione, umbelliprenin, conferone, feselol, lehmferin and farnesiferol B were isolated from the roots of Ferula flabelliloba Rech. f. & Aell. (Apiaceae). The structures of these compounds were elucidated by various 1- and 2-D NMR techniques as well as HREIMS.

Keywords::

• Ferula flabelliloba
• Apiaceae
• farnesiferone B
• flabellilobin A
• flabellilobin B

Acknowledgements

This research was supported by a grant from Mashhad University of Medical Sciences Research Council. We thank Sybille Lorenz (Jena) for mass spectrometric measurements.

Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.