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Research Article

Nutmeg Oil: Effect on Acute Amphetamine Intoxication

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Pages 89-92 | Published online: 27 Sep 2008
 

Abstract

The essential oil of nutmeg (600 or 900 mg/kg, IP) altered the young chicks' species-specific response to amphetamine (20 mg/kg, SQ). Nutmeg oil totally blocked the development of chirping and decreased the duration of wing droop and stereotyped behavior “b” (head and neck extended forward, parallel to but not touching floor), but increased the duration of stereotyped behavior “a” (head and neck drawn back with top of head almost touching back). Amphetamine caused a significant decrease in the duration of light and deep sleep in the group that received the higher dose level of nutmeg oil.

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