Isolation and Hypoglycemic Activity of Panaxans M, N, O and P, Glycans of Panax ginseng Roots

Abstract

A polysaccharide fraction of the Oriental crude drug “ninjin” (ginseng), Panax ginseng roots from China, significantly lowered blood sugar level in mice. Activity-guided fractionation of the fraction furnished four glycans, panaxans M, N, O and P, which exerted hypoglycemic effects in normal and alloxan-produced hyperglycemic mice.