(+)-Dihydroperfamine: An Alkaloid from Haplophyllum tuberculatum

Mohammed A. Al-Yahya Department of Pharmacognosy and Medicinal, Aromatic and Poisonous Plants Research Center, College of Pharmacy, Kind Saud University, P.O. Box 2457, Riyadh, 11451, Saudi Arabia

Maher M. El-Domiaty Department of Pharmacognosy and Medicinal, Aromatic and Poisonous Plants Research Center, College of Pharmacy, Kind Saud University, P.O. Box 2457, Riyadh, 11451, Saudi Arabia

Ibrahim A. Al-Meshal Department of Pharmacognosy and Medicinal, Aromatic and Poisonous Plants Research Center, College of Pharmacy, Kind Saud University, P.O. Box 2457, Riyadh, 11451, Saudi Arabia

Mansour S. Al-Said Department of Pharmacognosy and Medicinal, Aromatic and Poisonous Plants Research Center, College of Pharmacy, Kind Saud University, P.O. Box 2457, Riyadh, 11451, Saudi Arabia

Farouk S. El-Feraly Department of Pharmacognosy and Medicinal, Aromatic and Poisonous Plants Research Center, College of Pharmacy, Kind Saud University, P.O. Box 2457, Riyadh, 11451, Saudi Arabia

Abstract

Dihydroperfamine (I), partially enriched by its dextrorotatory enantiomer, has been isolated from a Saudi Arabian variant of Haplophyllum tuberculatum. Its structure was deduced from its physical and spectral data, and by direct comparison with the (-)-antipode. The profile of the other isolated constituents, justicidin A, justicidin B, 3-dimethyaUyl-4-dimethylallyloxy-2-quinolone and (+)-tuberine has been compared to those reported in other variants.

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(+)-Dihydroperfamine: An Alkaloid from Haplophyllum tuberculatum

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(+)-Dihydroperfamine: An Alkaloid from Haplophyllum tuberculatum

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