Antimicrobial Constituent of the Brown Alga Sporochnus pedunculatus

Abstract

Bioassay-guided fractionation of the ethanol extract of the brown alga Sporochnus pedunculatus led to the isolation of 2-(3′-methylbut-2′-enyl)-4- (1″, 1″-dimethylprop-2″ -enyl) phenol (1) as the only antimicrobial compound. This compound is a growth inhibitor of Candida albicans, Cryptococcus neoformans, and Bacillus subtilis. In this paper we report the isolation, identification, and biological activity of 1.

Keywords::

• Sporocnus pedunculatus
• brown alga
• diprenylated phenol
• antimicrobial activity
• NMR data