Multiple malignancies in a patient with limited granulomatosis with polyangiitis without immunosuppressive therapy

Abstract

Here, we report the case of a 69-year-old man with limited granulomatosis with polyangiitis (GPA; formerly Wegener's granulomatosis) who developed papillary thyroid cancer, adenocarcinoma of the stomach, and myelodysplastic syndrome following glucocorticoid treatment. This is the first report to present multiple malignancies in a patient with limited GPA without immunosuppressive treatment. Thus, our report supports the notion that limited GPA itself can be associated with the development of malignancy.

Keywords:

• ANCA
• Granulomatosis with polyangiitis
• Malignancy
• Myelodysplastic syndrome
• Vasculitis

Conflicts of interest

None.