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Short Communications

A new depsidone of Lobaria pulmonaria with acetylcholinesterase inhibition activity

, , , , &
Pages 876-878 | Received 10 Feb 2012, Accepted 08 Mar 2012, Published online: 18 Apr 2012
 

Abstract

The phytochemical investigation conducted on a foliose lichen, Lobaria pulmonaria(L.) Hoffm. (Lobariaceae), led to the isolation of a new depsidone in the form of its diacetate derivative which showed a moderate acetylcholinesterase inhibition activity (1 µg) in vitro. This is the first record of identified depsidone structure in searching for these inhibitors.

Acknowledgements

The assistance of Mr. V. Mirra of NMR Service CNR-ICB is gratefully acknowledged.

Declaration of interest

This work was supported by the Ministry of Science and Technological Development of the Republic of Serbia (Research grant Nos. 172053 and 173040).

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