Intraamniotic Infection with Candida tropicalis in Preterm Labor

Roberto Romero Section of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut, USA; Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, Michigan, USA; Intramural Branch of Perinatology, National Institutes of Health, Bethesda, Maryland, USA

Jose Nores Section of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut, USA

Zion Hagay Section of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut, USA

Cecilia Avila Section of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut, USA

Shuichi Hanaoka Section of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut, USA

Waldo Sepulveda Section of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut, USA; Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, Michigan, USA; Intramural Branch of Perinatology, National Institutes of Health, Bethesda, Maryland, USA

David B. Cotton Section of Maternal-Fetal Medicine, Department of Obstetrics and Gynecology, Yale University School of Medicine, New Haven, Connecticut, USA; Department of Obstetrics and Gynecology, Wayne State University School of Medicine, Detroit, Michigan, USA

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Abstract

Colonization of the amniotic cavity with Candida tropicalis was diagnosed in a woman with preterm labor and intact membranes. Treatment with ketoconazole and amphotericin B failed to eradicate the microorganism from the amniotic cavity. Tocolysis was administered and was considered successful in prolonging the pregnancy for 11 days after the initiation of treatment. There was no clinical or microbiological evidence of neonatal infection. The infant survived and was discharged home 2 months after birth.

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Intraamniotic Infection with Candida tropicalis in Preterm Labor

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Intraamniotic Infection with Candida tropicalis in Preterm Labor

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