Maternal Hyperoxygenation for the Treatment of Fetal Growth Retardation

Abstract

Maternal hyperoxygenation has been demonstrated to improve fetal pO₂, and was suggested as a treatment for intrauterine growth retardation. Our initial results with such treatment are presented. Four patients with fetal growth retardation were continuously treated with oxygen enriched air breathed through a face mask. Growth retardation was determined by sonographic estimates of low weight, increased head to abdominal circumference ratio, oligohydramnios, and abnormal resistance to flow in the umbilical artery. In all cases prolongation of pregnancy has become possible, doppler flow parameters have improved, and the immediate perinatal outcome was good. Additional clinical experience, with maternal hyperoxygenation, is needed before its usefulness in the treatment of intrauterine growth retardation can be determined.

Key Words:

• Intrauterine growth retardation
• Oxygen treatment