Idiopathic Granulomatous Angiitis of the Central Nervous System in Pregnancy

The First Case Report

Marcelo J. Barrionuevo Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Sinai Hospital, Wayne State University School of Medicine, Detroit, Michigan, USA; Department of Internal Medicine, Neurology Division, Sinai Hospital, Wayne State University School of Medicine, Detroit, Michigan, USA

Richard A. Bronsteen Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Sinai Hospital, Wayne State University School of Medicine, Detroit, Michigan, USA; Department of Internal Medicine, Neurology Division, Sinai Hospital, Wayne State University School of Medicine, Detroit, Michigan, USA

Lawrence M. Eilender Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Sinai Hospital, Wayne State University School of Medicine, Detroit, Michigan, USA; Department of Internal Medicine, Neurology Division, Sinai Hospital, Wayne State University School of Medicine, Detroit, Michigan, USA

Debra J. Wright Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Sinai Hospital, Wayne State University School of Medicine, Detroit, Michigan, USA; Department of Internal Medicine, Neurology Division, Sinai Hospital, Wayne State University School of Medicine, Detroit, Michigan, USA

Gregory L. Goyert Department of Obstetrics and Gynecology, Division of Maternal-Fetal Medicine, Sinai Hospital, Wayne State University School of Medicine, Detroit, Michigan, USA; Department of Internal Medicine, Neurology Division, Sinai Hospital, Wayne State University School of Medicine, Detroit, Michigan, USA

Abstract

Idiopathic granulomatous angiitis of the central nervous system (IGANS) is a rare vasculitis primarily affecting the spinal cord and brain not related to any underlying systemic disease. Clinical manifestations range from simple headache to cerebral vascular accidents secondary to vascular occlusion. The management of a pregnancy complicated by multiple risk factors including underlying IGANS is reported. An expectant, empiric approach was adopted and resulted in excellent maternal and neonatal outcomes. The first report of the management of a pregnancy complicated by IGANS is presented. Underlying maternal IGANS may not necessarily represent an indication for pregnancy termination.

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Idiopathic Granulomatous Angiitis of the Central Nervous System in Pregnancy

The First Case Report

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Idiopathic Granulomatous Angiitis of the Central Nervous System in Pregnancy

The First Case Report

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