Herpes Simplex Virus–Based Gene Therapies for Chronic Pain

Kristen WeissKristen Weiss Sanders, BS, is a graduate student researcher in neuroscience and Nicholas M. Boulis, MD, is an assistant professor at the Boulis Laboratory, Department of Neurosurgery, Emory University, Atlanta, Georgia, USACorrespondence[email protected]

Nicholas M. BoulisKristen Weiss Sanders, BS, is a graduate student researcher in neuroscience and Nicholas M. Boulis, MD, is an assistant professor at the Boulis Laboratory, Department of Neurosurgery, Emory University, Atlanta, Georgia, USA

ABSTRACT

The promise of gene therapy in chronic pain management is described. Use of the Herpes simplex virus to deliver such therapy is discussed. Clinical trials of gene-based therapy for neuropathic, cancer, and inflammatory pain are summarized. The potential role for such therapies are discussed.

This feature is adapted from paineurope 2012; Issue 1, ©Haymarket Medical Publications Ltd., and is presented with permission. paineurope is provided as a service to pain management by Mundipharma International, Ltd., and is distributed free of charge to health care professionals in Europe. Archival issues can be accessed via the Web site: http://www.paineurope.com at which European health professionals can register online to receive copies of the quarterly publication.

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Herpes Simplex Virus–Based Gene Therapies for Chronic Pain

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