Effect of the “zero” Magnetic Field on Early Embryogenesis in Mice

Abstract

It was shown that the 250-fold screening of the geomagnetic field (GMF) (“zero” magnetic field with an induction of 0.2 μT) affects early embryogenesis and the reproduction capacity of mice in vivo. Pregnant NMRI mice at the zygote stage placed in this “zero” magnetic field (MF) lost the ability to bear offspring babies although their embryos developed up to the blastocyst stage without any visible deviations from the norm. The abortion of development in the “zero” MF occurred after the exit of the blastocysts from the zona pellicida and invasion into the uterus during implantation. Histological analysis indicates that possible reasons of the abnormalities of postimplantation development are a decrease in the proliferative activity of embryonic cells and the impairment of the interaction between the trophoblast and endometrium, which finally results in the resorption of embryos in the uterus.

Keywords:

• Magnetic field
• Embryos
• Implantation
• Early embryogenesis of mammals

Declaration of Interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the article.