Transplacental Hemorrhage Associated with Placental Neoplasms

Monica Santamaria Department of Pathology, University of California at San Diego Medical Center, San Diego, California, 92103, USA

Kurt Benirschke Department of Pathology, University of California at San Diego Medical Center, San Diego, California, 92103, USA

Philip M. Carpenter Department of Pathology, University of California at San Diego Medical Center, San Diego, California, 92103, USA

Virginia J. Baldwin Department of Pathology, University of British Columbia, Vancouver, British Columbia, Canada, V6H 3V4

Jack A. Pritchard Department of Obstetrics and Gynecology, University of Texas Health Science Center at Dallas, Southwestern Medical School, Dallas, Texas, 75217, USA

Abstract

We report a case of choriocarcinoma in situ arising from a term placenta in an otherwise normal pregnancy that resulted in fetal hydrops and intrauterine fetal death from chronic fetal-maternal hemorrhage (FMH). The clinical and pathologic features are described and compared with the few similar cases reported and with an additional placental choriocarcinoma found in our files. We also describe the clinical and pathologic observations of two choran-giomas that caused massive FMH and led to fetal death.

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Transplacental Hemorrhage Associated with Placental Neoplasms

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Transplacental Hemorrhage Associated with Placental Neoplasms

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