Contact dermatitis caused by dimethylfumarate in Argentina

Abstract

For the first time in Argentina, we describe an outbreak of contact dermatitis. New pairs of shoes caused intense pruritus, pain, and eruption, followed by edema, blisters, and a severe negative impact on the epidermal barrier of the feet. We identify dimethylfumarate as the causal agent and suggest an analytical method for its fast identification.

Keywords:

• Skin
• Dimethylfumerate
• Contact dermatitis