Flumazenil for the Reversal of Refractory Benzodiazepine-Induced Shock

Abstract

Benzodiazepines are known to cause central nervous system and centrally mediated cardiovascular depression. The benzodiazepine antagonist flumazenil has been shown to antagonize benzodiazepine-induced central nervous system depression. We report a case in which cardiovascular depression secondary to benzodiazepine use was reversed by this agent.

KEY WORDS:

• flumazenil
• benzodiazepine-induced shock