Seizure with Hyponatremia in a Child Prescribed Desmopressin for Nocturnal Enuresis

Gildas Yaouyanc Department of Medicine, Hopital du Blanc, France

Annie Pierre Jonville Anti-Poisoning Center and Regional Drug Monitoring Center, Department of Pharmaco-Toxicovigilance, Hopital Bretonneau and University of Tours, Tours, France

Hélène Yaouyanc-Lapalle Department of Medicine, Hopital du Blanc, France

Pascaline Barbier Anti-Poisoning Center and Regional Drug Monitoring Center, Department of Pharmaco-Toxicovigilance, Hopital Bretonneau and University of Tours, Tours, France

Jean Paul Dutertre Anti-Poisoning Center and Regional Drug Monitoring Center, Department of Pharmaco-Toxicovigilance, Hopital Bretonneau and University of Tours, Tours, France

Elisabeth Autret Anti-Poisoning Center and Regional Drug Monitoring Center, Department of Pharmaco-Toxicovigilance, Hopital Bretonneau and University of Tours, Tours, France

Abstract

We report a case of hyponatremia associated with a grand mal seizure in a 28 month-old child after intra-nasal desmopressin administration for high fluid intake with nocturnal enuresis. In view of the temporary symptomatic action and the seriousness of certain side-effects of desmopressin we recommend that desmopressin be used with caution in childhood enuresis.

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Seizure with Hyponatremia in a Child Prescribed Desmopressin for Nocturnal Enuresis

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Seizure with Hyponatremia in a Child Prescribed Desmopressin for Nocturnal Enuresis

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