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Research Article

Toxic Polyneuropathy Due to Flour Contaminated with Tricresyl Phosphate in China

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Pages 373-374 | Published online: 25 Sep 2008
 

Abstract

The neurotoxic tricresyl phosphates (TCP) are odorless, colorless and stable compounds. The o-isomer of TCP is more toxic than the m- or p-isomers (1,2) and tri-ortho-cresyl phosphate (TOCP) is now a reference chemical for experimental organophosphorus induced delayed neurotoxicity (OPIDN), although it is not an organophosphorus pesticide (3). TCP mixtures (o, m- and p-isomers) are still used as plasticizers and flame-retardants in a variety of industrial and commercial preparations (primarily paints, lubricants, plastic, and hydraulic fluids).

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