Primary cutaneous anaplastic CD30⁺ large-cell lymphoma that completely regressed after incisional skin biopsy

Abstract

We describe a 48-year-old woman with three erythematous nodules localized on the left forearm, with 2 months evolution. Histological and immunohistochemical examination revealed a CD30⁺ large-cell lymphoma. Systemic involvement was not detected. The tumor regressed spontaneously within a week, after the incisional skin biopsy. In control skin biopsy, there was not any histological feature of lymphoma. No reactivation or any symptom of systemic disease was observed during the 10-month follow-up period.

Keywords::

• Cutaneous
• regression
• lymphoma
• large-cell
• CD30-positive
• anaplastic
• spontaneously