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Abstract
Ochratoxins are fungal secondary metabolites produced during storage by fungus of the genera Aspergillus, mainly in tropical and warmer regions and by Penicillium verrucosum, in temperate and colder areas. Ochratoxin A (OTA) displays a multiple toxicity, including immunotoxicity. Until present, there have been very few, sometimes contrasting, reports on the mechanisms underlying OTA immunotoxicity. In this review, we have summarized the researches done until present concerning the interaction between OTA and the immune response.
Acknowledgements
This work was financed through the project PN-II-RU-TE-2012-3-0086 financed by UEFISCDI.
Declaration of interest
The authors report no conflicts of interest. The authors alone are responsible for the content and writing of this article.
