Abstract
This article reviews the role of neutrophils in myocardial ischemia–reperfusion injury. A number of studies have demonstrated that myocardial ischemia–reperfusion injury is an acute inflammatory process in which neutrophils are involved by accumulating at the site of ischemia injury. This process requires signals and pro-inflammatory molecules to direct neutrophils to the site of ischemia, and cell adhesion molecules to connect them with the endothelium.