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Abstract
This paper presents a response to the Citation lead article regarding the accuracy and effectiveness of early identification and early intervention for young children with autism spectrum disorders (ASD). While Caramata focused heavily on the challenges of behavioural screening for ASD, we believe that he has overlooked the potential that the identification of ASD biomarkers may have for the early detection of the disorder. We propose that the discovery of biomarkers, particularly those that may be used in conjunction with behavioural screening, may provide an important next step in reliably detecting and accurately diagnosing ASD in the early years. This would have important clinical implications in terms of providing early intervention, which may alter the developmental path for the child.
Declaration of interest: The authors report no conflicts of interest. The authors alone are responsible for the content and writing of the paper.
Notes
1An ERP component represents the neural activation that is associated with certain behavioural or cognitive processes. ERPs are characterized by polarity (negative or positive), latency, and location. For example, a P100 component is a positive waveform that occurs 100 milliseconds after stimulus onset and is related to processing visual stimuli.