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Abstract
In the last few decades, various drug-delivery technologies have emerged and a fascinating part of this has been the development of nanoscale drug delivery devices. Nanoparticles (NPs) and other colloidal drug-delivery systems modify the kinetics, drug distribution in the body and release profile of an associated drug. Nanostructured lipid carriers (NLCs) have been reported to be an alternative system to emulsions, liposomes, microparticles, solid lipid nanoparticles (SLNs) and their polymeric counterparts due to their numerous advantages. This paper basically reviews the types of NLCs, mechanism of skin penetration, stability related issues along with their production techniques, characterisation and applications towards targeted drug delivery.
Acknowledgement
The authors are thankful to the Director, University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur (C.G.), India for the present study and All India Council of Technical Engineering (AICTE) and Department of Science and Technology (DST-FIST-SR/FST/LSI – 013/2010) and University Grant Commission [UGC SAP – F.3_54/2011(SAP 2)] for financial assistance.
Declaration of interest
The authors report no declarations of interest. The authors alone are responsible for the content and writing of the paper.