Ceramic nanoparticles: Recompense, cellular uptake and toxicity concerns

Abstract

Over the past few years, nanoparticles and their role in drug delivery have been the centre of attraction as new drug delivery systems. Various forms of nanosystems have been designed, such as nanoclays, scaffolds and nanotubes, having numerous applications in areas such as drug loading, target cell uptake, bioassay and imaging. The present study discusses various types of nanoparticles, with special emphasis on ceramic nanocarriers. Ceramic materials have high mechanical strength, good body response and low or non-existing biodegradability. In this article, the various aspects concerning ceramic nanoparticles, such as their advantages over other systems, their cellular uptake and toxicity concerns are discussed in detail.

Keywords::

• ceramic nanocarriers
• cellular uptake
• nanoparticles
• nanosystems
• toxicity

Acknowledgement

The authors are thankful to Director, University Institute of Pharmacy, Pt. Ravishankar Shukla University, Raipur (C.G.) India for this study and UGC-MRP-41-748-2012, UGC-RA 70-371/2012, DST-FIST for financial assistance relating to this work.

Declaration of interest

The authors report no declarations of interest. The authors alone are responsible for the content and writing of the paper.