Magnetic nanoparticles as potential candidates for biomedical and biological applications

Abstract

Magnetic iron oxide nanoparticles have become the main candidates for biomedical and biological applications, and the application of small iron oxide nanoparticles in in vitro diagnostics has been practiced for about half a century. Magnetic nanoparticles (MNPs), in combination with an external magnetic field and/or magnetizable grafts, allow the delivery of particles to the chosen target area, fix them at the local site while the medication is released, and act locally. In this review, we focus mostly on the potential use of MNPs for biomedical and biotechnological applications, and the improvements made in using these nanoparticles (NPs) in biological applications.

Keywords::

• iron oxide nanoparticles
• biotechnological applications
• diagnostics
• target

Authors’ contributions

AA conceived of the study and participated in its design and coordination. NN, FZS, and MN participated in the sequence alignment and drafted the manuscript. All authors read and approved the final manuscript.

Acknowledgments

The authors thank the Department of Medical Nanotechnology, Faculty of Advanced Medical Science of Tabriz University, for all support provided. This work is funded by the 2014 Drug Applied Research Center Tabriz University of Medical Sciences Grant.

Declaration of interest

The authors report no declarations of interest. The authors alone are responsible of the content and writing of the paper.