ABSTRACT
A teaching strategy that combines some aspects of traditional instruction with problem-based learning was developed and applied to basic and clinical pharmacokinetics courses. After a brief introduction to each topic by the instructor, the students utilize problems as the main tool in the learning process. Additionally, the method is outcome-based in that students are responsible for achieving outcomes and specific objectives for each topic. Student evaluations of the method in both large and small class sizes were strongly positive. Additionally, a comparison of grades during the recent years suggests a significant improvement in pharmacokinetics learning with implementation of the new strategy. The method offers some advantages over the traditional didactic lectures while being less resource-intensive than most problem-based learning strategies.