Sarcoid myositis with muscle weakness as a presenting symptom

Hideyasu YamadaClinical Immunology, Advanced Biomedical Applications, Graduate School of Comprehensive Human Sciences, University of Tsukuba,1-1-1 Tennodai, Tsukuba 305-8575, Japan

Wataru IshiiClinical Immunology, Advanced Biomedical Applications, Graduate School of Comprehensive Human Sciences, University of Tsukuba,1-1-1 Tennodai, Tsukuba 305-8575, Japan

Satoshi ItoClinical Immunology, Advanced Biomedical Applications, Graduate School of Comprehensive Human Sciences, University of Tsukuba,1-1-1 Tennodai, Tsukuba 305-8575, JapanCorrespondence[email protected]

Keiichi IwanamiClinical Immunology, Advanced Biomedical Applications, Graduate School of Comprehensive Human Sciences, University of Tsukuba,1-1-1 Tennodai, Tsukuba 305-8575, Japan

Hiroshi OgishimaClinical Immunology, Advanced Biomedical Applications, Graduate School of Comprehensive Human Sciences, University of Tsukuba,1-1-1 Tennodai, Tsukuba 305-8575, Japan

Takeshi SuzukiClinical Immunology, Advanced Biomedical Applications, Graduate School of Comprehensive Human Sciences, University of Tsukuba,1-1-1 Tennodai, Tsukuba 305-8575, Japan

Mizuko MamuraClinical Immunology, Advanced Biomedical Applications, Graduate School of Comprehensive Human Sciences, University of Tsukuba,1-1-1 Tennodai, Tsukuba 305-8575, Japan

Daisuke GotoClinical Immunology, Advanced Biomedical Applications, Graduate School of Comprehensive Human Sciences, University of Tsukuba,1-1-1 Tennodai, Tsukuba 305-8575, Japan

Isao MatsumotoClinical Immunology, Advanced Biomedical Applications, Graduate School of Comprehensive Human Sciences, University of Tsukuba,1-1-1 Tennodai, Tsukuba 305-8575, Japan

Akito TsutsumiClinical Immunology, Advanced Biomedical Applications, Graduate School of Comprehensive Human Sciences, University of Tsukuba,1-1-1 Tennodai, Tsukuba 305-8575, Japan

Takayuki SumidaClinical Immunology, Advanced Biomedical Applications, Graduate School of Comprehensive Human Sciences, University of Tsukuba,1-1-1 Tennodai, Tsukuba 305-8575, Japan

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Abstract

A 54-year-old woman complaining of muscle weakness and weight loss was admitted to our hospital with suspected polymyositis. Muscle biopsy revealed Langhans-type giant cells and noncaseating granulomas. Therefore, sarcoid myositis was diagnosed. The patient was treated with prednisolone, and the symptoms improved gradually. Generally, sarcoidosis is identified clinically in patients with foggy vision or mediastinal lymphadenopathy, but muscular weakness may be an infrequently observed initial symptom. Sarcoidosis should be considered in the differential diagnosis of polymyositis.

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Sarcoid myositis with muscle weakness as a presenting symptom

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Sarcoid myositis with muscle weakness as a presenting symptom

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