Citations (83)
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Konstantinos Anagnostakos & Bernd Fink. (2018) Antibiotic-loaded cement spacers – lessons learned from the past 20 years. Expert Review of Medical Devices 15:3, pages 231-245.
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Alexia James & Trent Larson. (2015) Acute renal failure after high-dose antibiotic bone cement: case report and review of the literature. Renal Failure 37:6, pages 1061-1066.
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Otto S Kluin, Henny C van der Mei, Henk J Busscher & Daniëlle Neut. (2013) Biodegradable vs non-biodegradable antibiotic delivery devices in the treatment of osteomyelitis. Expert Opinion on Drug Delivery 10:3, pages 341-351.
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Geert H I M Walenkamp. (2009) Self-mixed antibiotic bone cement: western countries learn from developing countries. Acta Orthopaedica 80:5, pages 505-507.
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Articles from other publishers (79)
William Steadman, Paul R. Chapman, Michael Schuetz, Beat Schmutz, Andrej Trampuz & Kevin Tetsworth. (2023) Local Antibiotic Delivery Options in Prosthetic Joint Infection. Antibiotics 12:4, pages 752.
Crossref
Crossref
Wenbo Mu, Baochao Ji & Li Cao. (2023) Single-stage revision for chronic periprosthetic joint infection after knee and hip arthroplasties: indications and treatments. Arthroplasty 5:1.
Crossref
Crossref
Meng-Wei Chang, Cheng-Ta Wu, Shih-Hsiang Yen, Timothy L. Tan, Po-Chun Lin & Feng-Chih Kuo. (2023) Influence of the Type of Bone Cement Used in Two-Stage Exchange Arthroplasty for Chronic Periarticular Joint Infection on the Spacer Replacement and Reinfection Rate. Journal of Clinical Medicine 12:2, pages 600.
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Crossref
Gregor Dersch & Heinz Winkler. (2022) Periprosthetic Joint Infection (PJI)—Results of One-Stage Revision with Antibiotic-Impregnated Cancellous Allograft Bone—A Retrospective Cohort Study. Antibiotics 11:3, pages 310.
Crossref
Crossref
Gladius Lewis. 2022. Essentials of Cemented Knee Arthroplasty. Essentials of Cemented Knee Arthroplasty
549
557
.
Matthew W. Squire. 2022. Essentials of Cemented Knee Arthroplasty. Essentials of Cemented Knee Arthroplasty
529
540
.
Daniel Pérez-Prieto. 2022. Infection in Knee Replacement. Infection in Knee Replacement
303
311
.
Aliya Sharipova, Ronald E. Unger, Alejandro Sosnik & Elazar Gutmanas. (2021) Dense drug-eluting biodegradable Fe-Ag nanocomposites. Materials & Design 204, pages 109660.
Crossref
Crossref
Victoria Wall, Thi-Hiep Nguyen, Nghi Nguyen & Phong A. Tran. (2021) Controlling Antibiotic Release from Polymethylmethacrylate Bone Cement. Biomedicines 9:1, pages 26.
Crossref
Crossref
Eva Klapkova, Monika Nescakova, Pavel Melichercik, David Jahoda, Katerina Dunovska, Jana Cepova & Richard Prusa. (2019) Vancomycin and its crystalline degradation products released from bone grafts and different types of bone cement. Folia Microbiologica 65:3, pages 475-482.
Crossref
Crossref
Erik C. Bowman & Arthur L. Malkani. (2020) Point/Counterpoint: Static vs Articulating Spacers—Static Spacers for Resection Arthroplasty of the Knee. The Journal of Arthroplasty 35:3, pages S35-S39.
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Crossref
Erika L. Cyphert, Chao-yi Lu, Dylan W. Marques, Greg D. Learn & Horst A. von Recum. (2019) Combination Antibiotic Delivery in PMMA Provides Sustained Broad-Spectrum Antimicrobial Activity and Allows for Postimplantation Refilling. Biomacromolecules 21:2, pages 854-866.
Crossref
Crossref
Jake A. Mooney, Robert Manasherob, Piera Smeriglio, Nidhi Bhutani & Derek F. Amanatullah. (2019) Effect of trabecular metal on the elution of gentamicin from Palacos cement. Journal of Orthopaedic Research 37:5, pages 1018-1024.
Crossref
Crossref
B. JiT. WahafuG. LiX. ZhangY. WangM. MominL. Cao. (2019) Single-stage treatment of chronically infected total hip arthroplasty with cementless reconstruction. The Bone & Joint Journal 101-B:4, pages 396-402.
Crossref
Crossref
Myra E. Durham & Johanna R. Elfenbein. (2019) Evaluation of vaporized hydrogen peroxide sterilization on the in vitro efficacy of meropenem-impregnated polymethyl methacrylate beads. American Journal of Veterinary Research 80:1, pages 45-50.
Crossref
Crossref
Jeffrey Sundblad, Mary Nixon, Nancy Jackson, Rahul Vaidya & David Markel. (2018) Altering polymerization temperature of antibiotic-laden cement can increase porosity and subsequent antibiotic elution. International Orthopaedics 42:11, pages 2627-2632.
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Crossref
Jong Ho NohSung Jun KohKee Haeng Lee. (2018) Treatment of Proximal Femur Osteomyelitis Occurred after Proximal Femoral Nail Antirotation Fixation, with Antibiotic Cement-coated Tibia Intramedullary Nail: A Case Report. Hip & Pelvis 30:1, pages 45.
Crossref
Crossref
Yue Sa, Fang Yang, Yining Wang, Joop G. C. Wolke & John A. Jansen. 2018. Cutting-Edge Enabling Technologies for Regenerative Medicine. Cutting-Edge Enabling Technologies for Regenerative Medicine
119
134
.
Karim A. Elsharkawy & Carl T. Talmo. 2018. Revision Total Knee Arthroplasty. Revision Total Knee Arthroplasty
263
273
.
Stephen M. Petis, Kevin I. Perry, Mark W. Pagnano, Daniel J. Berry, Arlen D. Hanssen & Matthew P. Abdel. (2017) Retained Antibiotic Spacers After Total Hip and Knee Arthroplasty Resections: High Complication Rates. The Journal of Arthroplasty 32:11, pages 3510-3518.
Crossref
Crossref
CJ O’Dowd-Booth, SF Bellringer, C Gee & P Stott. (2017) Introduction of antibiotic-loaded cement during hip hemiarthroplasty washout to reduce the need for full revision surgery. The Annals of The Royal College of Surgeons of England 99:7, pages 584-584.
Crossref
Crossref
Matthew R. Karek, Nancy M. Jackson, Jeffrey C. Flynn, Rahul Vaidya & David C. Markel. (2017) Elution Profiles of Two Methods of Antibiotic Tibial Nail Preparations. Orthopedics 40:3.
Crossref
Crossref
Danir Fanisovich Bayramov & Jennifer Ann Neff. (2017) Beyond conventional antibiotics — New directions for combination products to combat biofilm. Advanced Drug Delivery Reviews 112, pages 48-60.
Crossref
Crossref
MARYAM KALANTARI & ATA HASHEMI. (2017) EFFECT OF ANTIBIOTICS AUGMENTATION AND STORAGE CONDITION ON IMPACT RESISTANCE OF ORTHOPEDIC BONE CEMENT. Journal of Mechanics in Medicine and Biology 17:01, pages 1750019.
Crossref
Crossref
Konstantinos Anagnostakos & Christof Meyer. (2017) Antibiotic Elution from Hip and Knee Acrylic Bone Cement Spacers: A Systematic Review. BioMed Research International 2017, pages 1-7.
Crossref
Crossref
Shin Xu, Brent A. Ponce, Peter G. Pavlidakey & Eugene W. BrabstonIIIIII. (2016) Drug eruption secondary to vancomycin-laden spacer in the shoulder: a case report. Journal of Shoulder and Elbow Surgery 25:8, pages e236-e240.
Crossref
Crossref
José Luis Rodrigo-Pérez, Carlos Daniel Novoa-Parra, José Manuel Pelayo de Tomás, José Antonio Blas Dobón & Maria Morales Suárez-Varea. (2016) Uso del cemento con antibióticos como profilaxis en artroplastias de cadera: revisión de la bibliografía. Revista Latinoamericana de Cirugía Ortopédica 1:3, pages 108-115.
Crossref
Crossref
Mark J. Gage, Richard S. Yoon, Robert J. Gaines, Robert P. Dunbar, Kenneth A. Egol & Frank A. Liporace. (2016) Dead Space Management After Orthopaedic Trauma. Journal of Orthopaedic Trauma 30:2, pages 64-70.
Crossref
Crossref
Lauren Kiri, Mark Filiaggi & Daniel Boyd. (2015) Methotrexate-loaded glass ionomer cements for drug release in the skeleton: An examination of composition–property relationships. Journal of Biomaterials Applications 30:6, pages 732-739.
Crossref
Crossref
Shou-Cang Shen, Wai Kiong Ng, Yuan-Cai Dong, Junwei Ng & Reginald Beng Hee Tan. (2016) Nanostructured material formulated acrylic bone cements with enhanced drug release. Materials Science and Engineering: C 58, pages 233-241.
Crossref
Crossref
Volker Alt, Jörg Franke & Reinhard Schnettler. (2015) Local Delivery of Antibiotics in the Surgical Treatment of Bone Infections. Techniques in Orthopaedics 30:4, pages 230-235.
Crossref
Crossref
S. SalihA. PaskinsT. NicholT. SmithA. Hamer. (2015) The cement spacer with multiple indentations. The Bone & Joint Journal 97-B:11, pages 1519-1524.
Crossref
Crossref
Ferdi Hizal, Iryna Zhuk, Svetlana Sukhishvili, Henk J. Busscher, Henny C. van der Mei & Chang-Hwan Choi. (2015) Impact of 3D Hierarchical Nanostructures on the Antibacterial Efficacy of a Bacteria-Triggered Self-Defensive Antibiotic Coating. ACS Applied Materials & Interfaces 7:36, pages 20304-20313.
Crossref
Crossref
Javier Martínez-Moreno, Carla Mura, Virginia Merino, Amparo Nácher, Mónica Climente & Matilde Merino-Sanjuán. (2015) Study of the Influence of Bone Cement Type and Mixing Method on the Bioactivity and the Elution Kinetics of Ciprofloxacin. The Journal of Arthroplasty 30:7, pages 1243-1249.
Crossref
Crossref
Benjamin D. Brooks, Kristofer D. Sinclair, David W. Grainger & Amanda E. Brooks. (2015) A Resorbable Antibiotic-Eluting Polymer Composite Bone Void Filler for Perioperative Infection Prevention in a Rabbit Radial Defect Model. PLOS ONE 10:3, pages e0118696.
Crossref
Crossref
G. Massazza, A. Bistolfi, E. Verné, M. Miola, L. Ravera & F. Rosso. 2015. Biomaterials and Medical Device - Associated Infections. Biomaterials and Medical Device - Associated Infections
185
197
.
Marcin K. Wasko & Rafal Kaminski. (2015) Custom-Made Antibiotic Cement Nails in Orthopaedic Trauma: Review of Outcomes, New Approaches, and Perspectives. BioMed Research International 2015, pages 1-12.
Crossref
Crossref
Hye Sun Lee & Jeong Ho Chang. (2015) Antimicrobial spine-bone cement with caffeic acid phenethyl ester for controlled release formulation and in vivo biological assessments. MedChemComm 6:2, pages 327-333.
Crossref
Crossref
Suzanne Stewart, Stephanie J. Bryant, Jaimo Ahn & Kurt D. Hankenson. 2015. Translational Regenerative Medicine. Translational Regenerative Medicine
313
333
.
Gladius Lewis. (2015) Not all approved antibiotic-loaded PMMA bone cement brands are the same: ranking using the utility materials selection concept. Journal of Materials Science: Materials in Medicine 26:1.
Crossref
Crossref
Iolanda Francolini, Gianfranco Donelli, Fernanda Crisante, Vincenzo Taresco & Antonella Piozzi. 2015. Biofilm-based Healthcare-associated Infections. Biofilm-based Healthcare-associated Infections
93
117
.
N. Bormann, P. Schwabe, M.D. Smith & B. Wildemann. (2014) Analysis of parameters influencing the release of antibiotics mixed with bone grafting material using a reliable mixing procedure. Bone 59, pages 162-172.
Crossref
Crossref
Khalid Azzam, Curtis Hartman & Kevin Garvin. 2014. Periprosthetic Joint Infection of the Hip and Knee. Periprosthetic Joint Infection of the Hip and Knee
187
191
.
J. GALLO, K. BOGDANOVÁ, M. ŠILLER, M. ŠVÁBOVÁ, J. LOŠŤÁK & M. KOLÁŘ. (2013) Microbial and Pharmacological Characteristics of VancogenX. Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca 80:1, pages 69-76.
Crossref
Crossref
Jenneke J. Deelstra, Danielle Neut & Paul C. Jutte. (2013) Successful Treatment of Candida Albicans–Infected Total Hip Prosthesis With Staged Procedure Using an Antifungal-Loaded Cement Spacer. The Journal of Arthroplasty 28:2, pages 374.e5-374.e8.
Crossref
Crossref
Benjamin D. Brooks, Amanda E. Brooks & David W. Grainger. 2013. Biomaterials Associated Infection. Biomaterials Associated Infection
307
354
.
Tanay J. Amin, Jeffrey W. Lamping, Kelly J. Hendricks & Terence E. McIff. (2012) Increasing the Elution of Vancomycin from High-Dose Antibiotic-Loaded Bone Cement: A Novel Preparation Technique. Journal of Bone and Joint Surgery 94:21, pages 1946-1951.
Crossref
Crossref
Curtis Hartman, Angela Hewlett & Kevin Garvin. (2012) The pharmacology of infection after total joint arthroplasty. Current Orthopaedic Practice 23:6, pages 529-532.
Crossref
Crossref
Jacques Tabutin, Thomas D'Ollonne & Pierre M. Cambas. (2012) Antibiotic Addition to Cement - is it Beneficial?. HIP International 22:1, pages 9-12.
Crossref
Crossref
S. Travis King, Justin B. Usery & Kerry O. Cleveland. (2011) Adverse renal outcomes associated with antibiotic-laden spacers in two-stage joint revisions. Journal of Infection 63:6, pages 471-473.
Crossref
Crossref
Jill Meyer, Geoff Piller, Carol A. Spiegel, Scott Hetzel & Matthew Squire. (2011) Vacuum-Mixing Significantly Changes Antibiotic Elution Characteristics of Commercially Available Antibiotic-Impregnated Bone Cements. Journal of Bone and Joint Surgery 93:22, pages 2049-2056.
Crossref
Crossref
Alessandro Bistolfi, Giuseppe Massazza, Enrica Verné, Alessandro Massè, Davide Deledda, Sara Ferraris, Marta Miola, Fabrizio Galetto & Maurizio Crova. (2011) Antibiotic-Loaded Cement in Orthopedic Surgery: A Review. ISRN Orthopedics 2011, pages 1-8.
Crossref
Crossref
Leo A. Whiteside, Michael Peppers, Tariq A. Nayfeh & Marcel E. Roy. (2010) Methicillin-resistant Staphylococcus aureus in TKA Treated With Revision and Direct Intraarticular Antibiotic Infusion. Clinical Orthopaedics and Related Research® 469:1, pages 26-33.
Crossref
Crossref
Daniëlle Neut, Otto S Kluin, Jonathan Thompson, Henny C van der Mei & Henk J Busscher. (2010) Gentamicin release from commercially-available gentamicin-loaded PMMA bone cements in a prosthesis-related interfacial gap model and their antibacterial efficacy. BMC Musculoskeletal Disorders 11:1.
Crossref
Crossref
Hugh S. Brock, Patrick G. Moodie, Kelly J. Hendricks & Terence E. McIff. (2010) Compression Strength and Porosity of Single-Antibiotic Cement Vacuum-Mixed With Vancomycin. The Journal of Arthroplasty 25:6, pages 990-997.
Crossref
Crossref
McKinley C. Lawson, Kevin C. Hoth, Cole A. DeForest, Christopher N. Bowman & Kristi S. Anseth. (2010) Inhibition of Staphylococcus epidermidis Biofilms Using Polymerizable Vancomycin Derivatives. Clinical Orthopaedics and Related Research® 468:8, pages 2081-2091.
Crossref
Crossref
D. FARRAR, R. BENSON & R. MILNER. 2010. Drug-Device Combination Products. Drug-Device Combination Products
190
218
.
Valerie L. Schade & Thomas S. Roukis. (2010) The Role of Polymethylmethacrylate Antibiotic–loaded Cement in Addition to Debridement for the Treatment of Soft Tissue and Osseous Infections of the Foot and Ankle. The Journal of Foot and Ankle Surgery 49:1, pages 55-62.
Crossref
Crossref
Alex C. McLaren, Matt Nugent, Kostas Economopoulos, Himanshu Kaul, Brent L. Vernon & Ryan McLemore. (2009) Hand-mixed and Premixed Antibiotic-loaded Bone Cement Have Similar Homogeneity. Clinical Orthopaedics & Related Research 467:7, pages 1693-1698.
Crossref
Crossref
Konstantinos Anagnostakos & Jens Kelm. (2009) Enhancement of antibiotic elution from acrylic bone cement. Journal of Biomedical Materials Research Part B: Applied Biomaterials 90B:1, pages 467-475.
Crossref
Crossref
Gladius Lewis. (2008) Properties of antibiotic‐loaded acrylic bone cements for use in cemented arthroplasties: A state‐of‐the‐art review. Journal of Biomedical Materials Research Part B: Applied Biomaterials 89B:2, pages 558-574.
Crossref
Crossref
Alec C. Stall, Ed Becker, Steven C. Ludwig, Daniel Gelb & Kornelis A. Poelstra. (2009) Reduction of Postoperative Spinal Implant Infection Using Gentamicin Microspheres. Spine 34:5, pages 479-483.
Crossref
Crossref
Pang-Hsin Hsieh, Ching-Lung Tai, Po-Chen Lee & Yu-Han Chang. (2009) Liquid Gentamicin and Vancomycin in Bone Cement. The Journal of Arthroplasty 24:1, pages 125-130.
Crossref
Crossref
J. RODERICK DAVEY & RAJIV GANDHI. 2009. Evidence-Based Orthopaedics. Evidence-Based Orthopaedics
556
560
.
Matthew W. Squire, Brian J. Ludwig, Jonathan R. Thompson, Jason Jagodzinski, Derek Hall & David Andes. (2008) Premixed Antibiotic Bone Cement. The Journal of Arthroplasty 23:6, pages 110-114.
Crossref
Crossref
S. DEB & G. KOLLER. 2008. Orthopaedic Bone Cements. Orthopaedic Bone Cements
313
331
.
Stephan Rupprecht, Ljubinko Petrovic, Bettina Burchhardt, Jörg Wiltfang, Friedrich Wilhelm Neukam & Karl Andreas Schlegel. (2007) Antibiotic‐containing collagen for the treatment of bone defects. Journal of Biomedical Materials Research Part B: Applied Biomaterials 83B:2, pages 314-319.
Crossref
Crossref
Y. Qiu, N. Zhang, Y. H. An & X. Wen. (2018) Biomaterial Strategies to Reduce Implant-Associated Infections. The International Journal of Artificial Organs 30:9, pages 828-841.
Crossref
Crossref
Quanjun Cui, William M. Mihalko, John S. Shields, Michael Ries & Khaled J. Saleh. (2007) Antibiotic-Impregnated Cement Spacers for the Treatment of Infection Associated with Total Hip or Knee Arthroplasty. The Journal of Bone and Joint Surgery-American Volume 89:4, pages 871-882.
Crossref
Crossref
R. Soffiatti. 2007. Infection and Local Treatment in Orthopedic Surgery. Infection and Local Treatment in Orthopedic Surgery
112
120
.
William A. Jiranek, Arlen D. Hanssen & A. Seth Greenwald. (2006) Antibiotic-Loaded Bone Cement for Infection Prophylaxis in Total Joint Replacement. The Journal of Bone & Joint Surgery 88:11, pages 2487-2500.
Crossref
Crossref
WILLIAM A. JIRANEK, ARLEN D. HANSSEN & A. SETH GREENWALD. (2006) ANTIBIOTIC-LOADED BONE CEMENT FOR INFECTION PROPHYLAXIS IN TOTAL JOINT REPLACEMENT. The Journal of Bone and Joint Surgery-American Volume 88:11, pages 2487-2500.
Crossref
Crossref
Pang‐Hsin Hsieh, Yu‐Han Chang, Shih‐Hao Chen, Steve W.N. Ueng & Chun‐Hsiung Shih. (2006) High concentration and bioactivity of vancomycin and aztreonam eluted from Simplex™ cement spacers in two‐stage revision of infected hip implants: A study of 46 patients at an average follow‐up of 107 days. Journal of Orthopaedic Research 24:8, pages 1615-1621.
Crossref
Crossref
Geert T. Ensing, Johannes G.E. Hendriks, Jelmer E. Jongsma, Jim R. van Horn, Henny C. van der Mei & Henk J. Busscher. (2005) The influence of ultrasound on the release of gentamicin from antibiotic‐loaded acrylic beads and bone cements. Journal of Biomedical Materials Research Part B: Applied Biomaterials 75B:1, pages 1-5.
Crossref
Crossref
Tore Dalén & Kjell G. Nilsson. (2005) VersaBond bone cement. The Knee 12:4, pages 311-317.
Crossref
Crossref
Jiří Gallo, Milan Kolář, Anthony V. Florschütz, Radek Novotný, Roman Pantůček & Michaela Kesselová. (2005) IN VITRO TESTING OF GENTAMICIN-VANCOMYCIN LOADED BONE CEMENT TO PREVENT PROSTHETIC JOINT INFECTION. Biomedical Papers 149:1, pages 153-158.
Crossref
Crossref
Gladius Lewis, Si Janna & Anuradha Bhattaram. (2005) Influence of the method of blending an antibiotic powder with an acrylic bone cement powder on physical, mechanical, and thermal properties of the cured cement. Biomaterials 26:20, pages 4317-4325.
Crossref
Crossref
Jian-Sheng Wang. 2005. The Well-Cemented Total Hip Arthroplasty. The Well-Cemented Total Hip Arthroplasty
107
112
.
Lehel Bálint, Béla Kocsis, Zalán Szántó & György Szabó. (2004) In vitro Measurement of the Time-Related Efficacy of Gentamicin Sulfate Release from Bone Cements. Chemotherapy 50:6, pages 302-307.
Crossref
Crossref