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Original Article

Role of MMP-9 and its tissue inhibitor TIMP-1 in human osteosarcoma
Findings in 42 patients followed for 1–16 years

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Pages 487-491 | Published online: 20 Jul 2009

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Colin Kong & Marc F Hansen. (2009) Biomarkers in osteosarcoma. Expert Opinion on Medical Diagnostics 3:1, pages 13-23.
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Articles from other publishers (40)

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Cheng‐long Chen, Long Zhang, Yu‐rui Jiao, Yi Zhou, Qiao‐feng Ge, Peng‐cui Li, Xiao‐juan Sun & Zhi Lv. (2019) miR‐134 inhibits osteosarcoma cell invasion and metastasis through targeting MMP 1 and MMP 3 in vitro and in vivo . FEBS Letters 593:10, pages 1089-1101.
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Jian Zhou, Tang Liu & Wanchun Wang. (2018) Prognostic significance of matrix metalloproteinase 9 expression in osteosarcoma. Medicine 97:44, pages e13051.
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Rosalia de Necochea-Campion, Lee M. Zuckerman, Hamid R. Mirshahidi, Shahrzad Khosrowpour, Chien-Shing Chen & Saied Mirshahidi. (2017) Metastatic biomarkers in synovial sarcoma. Biomarker Research 5:1.
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Rocio K. Rivera-Valentin, Limin Zhu & Dennis P. M. Hughes. (2015) Bone Sarcomas in Pediatrics: Progress in Our Understanding of Tumor Biology and Implications for Therapy. Pediatric Drugs 17:4, pages 257-271.
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WENQING LIANG, BO GAO, GUOJIAN XU, DONG WENG, MINGHUA XIE & YU QIAN. (2014) Possible contribution of aminopeptidase N (APN/CD13) to migration and invasion of human osteosarcoma cell lines. International Journal of Oncology 45:6, pages 2475-2485.
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Qiang Wang, Jun Cai, Jingcheng Wang, Chuanzhi Xiong & Jianning Zhao. (2014) MiR-143 inhibits EGFR-signaling-dependent osteosarcoma invasion. Tumor Biology 35:12, pages 12743-12748.
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Rama Garimella, Laurie Washington, Janalee Isaacson, Julian Vallejo, Madoka Spence, Ossama Tawfik, Peter Rowe, Marco Brotto & Raymond Perez. (2014) Extracellular Membrane Vesicles Derived from 143B Osteosarcoma Cells Contain Pro-Osteoclastogenic Cargo: A Novel Communication Mechanism in Osteosarcoma Bone Microenvironment. Translational Oncology 7:3, pages 331-340.
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Jir-You Wang, Po-Kuei Wu, Paul Chih-Hsueh Chen, Chuen-Chuan Yen, Giun-Yi Hung, Cheng-Fong Chen, Shih-Chieh Hung, Shih-Fen Tsai, Chien-Lin Liu, Tain-Hsiung Chen & Wei-Ming Chen. (2014) Manipulation Therapy Prior to Diagnosis Induced Primary Osteosarcoma Metastasis—From Clinical to Basic Research. PLoS ONE 9:5, pages e96571.
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Riccardo Di Fiore, Michela Marcatti, Rosa Drago-Ferrante, Antonella D'Anneo, Michela Giuliano, Daniela Carlisi, Anna De Blasio, Francesca Querques, Lucio Pastore, Giovanni Tesoriere & Renza Vento. (2014) Mutant p53 gain of function can be at the root of dedifferentiation of human osteosarcoma MG63 cells into 3AB-OS cancer stem cells. Bone 60, pages 198-212.
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Hyun Kee YangKwang Cheul JeongYang Kyung KimSung Taek Jung. (2014) Role of Matrix Metalloproteinase (MMP) 2 and MMP-9 in Soft Tissue Sarcoma. Clinics in Orthopedic Surgery 6:4, pages 443.
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Rui Niimi, Akihiko Matsumine, Takahiro Iino, Shigeto Nakazora, Tomoki Nakamura, Atsumasa Uchida & Akihiro Sudo. (2013) Soluble Neural-cadherin as a novel biomarker for malignant bone and soft tissue tumors. BMC Cancer 13:1.
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A. Niedzwiecki. (2013) In vitro modulation of MMP-2 and MMP-9 in pediatric human sarcoma cell lines by cytokines, inducers and inhibitors. International Journal of Oncology.
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HUI-JYE CHEN, CHUNG-MING LIN, CHAO-YING LEE, NAI-CHEN SHIH, SHU-FEN PENG, MINORU TSUZUKI, SAKAE AMAGAYA, WEN-WEN HUANG & JAI-SING YANG. (2013) Kaempferol suppresses cell metastasis via inhibition of the ERK-p38-JNK and AP-1 signaling pathways in U-2 OS human osteosarcoma cells. Oncology Reports 30:2, pages 925-932.
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Aleksandra Niedzwiecki. (2013) Modulation of u-PA, MMPs and their inhibitors by a novel nutrient mixture in pediatric human sarcoma cell lines. International Journal of Oncology.
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Birgit Lohberger, Beate Rinner, Nicole Stuendl, Heike Kaltenegger, Bibiane Steinecker-Frohnwieser, Eva Bernhart, Ehsan Bonyadi Rad, Annelie Martina Weinberg, Andreas Leithner, Rudolf Bauer & Nadine Kretschmer. (2013) Sesquiterpene Lactones Downregulate G2/M Cell Cycle Regulator Proteins and Affect the Invasive Potential of Human Soft Tissue Sarcoma Cells. PLoS ONE 8:6, pages e66300.
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Atta Goudarzi, Nalan Gokgoz, Mona Gill, Dushanthi Pinnaduwage, Daniele Merico, Jay Wunder & Irene Andrulis. (2013) Protein Kinase C Epsilon and Genetic Networks in Osteosarcoma Metastasis. Cancers 5:4, pages 372-403.
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Knut Husmann, Matthias J.E. Arlt, Roman Muff, Bettina Langsam, Josefine Bertz, Walter Born & Bruno Fuchs. (2013) Matrix Metalloproteinase 1 promotes tumor formation and lung metastasis in an intratibial injection osteosarcoma mouse model. Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease 1832:2, pages 347-354.
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Jarkko T. Korpi, Jaana Hagström, Niko Lehtonen, Jyrki Parkkinen, Timo Sorsa, Tuula Salo & Minna Laitinen. (2011) Expression of matrix metalloproteinases-2, -8, -13, -26, and tissue inhibitors of metalloproteinase-1 in human osteosarcoma. Surgical Oncology 20:1, pages e18-e22.
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N. E. Kushlinsky, Yu. N. Solovyov, I. V. Babkina, E. S. Gershtein & I. V. Bulicheva. (2010) Matrix Metalloproteinases 2, 7, 9 and Tissue Inhibitor of Matrix Metalloproteinase-1 in the Sera of Patients with Bone Tumors. Bulletin of Experimental Biology and Medicine 149:2, pages 233-235.
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Yuxi Su, Xiaoji Luo, Bai-Cheng He, Yi Wang, Liang Chen, Guo-Wei Zuo, Bo Liu, Yang Bi, Jiayi Huang, Gao-Hui Zhu, Yun He, Quan Kang, Jinyong Luo, Jikun Shen, Jin Chen, Xianqing Jin, Rex C. Haydon, Tong-Chuan He & Hue H. Luu. (2009) Establishment and characterization of a new highly metastatic human osteosarcoma cell line. Clinical & Experimental Metastasis 26:7, pages 599-610.
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A. Reza Radjabi, Kenjiro Sawada, Sujatha Jagadeeswaran, Alfred Eichbichler, Hilary A. Kenny, Anthony Montag, Katharina Bruno & Ernst Lengyel. (2008) Thrombin Induces Tumor Invasion through the Induction and Association of Matrix Metalloproteinase-9 and β1-Integrin on the Cell Surface. Journal of Biological Chemistry 283:5, pages 2822-2834.
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Nancy Gordon, Nadezhda V. Koshkina, Shu-Fang Jia, Chand Khanna, Arnulfo Mendoza, Laura L. Worth & Eugenie S. Kleinerman. (2007) Corruption of the Fas Pathway Delays the Pulmonary Clearance of Murine Osteosarcoma Cells, Enhances Their Metastatic Potential, and Reduces the Effect of Aerosol Gemcitabine. Clinical Cancer Research 13:15, pages 4503-4510.
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Antony S. Moore, William S. Dernell, Gregory K. Ogilvie, Orna Kristal, Robyn Elmslie, Barbara Kitchell, Steven Susaneck, Robert Rosenthal, Mary K. Klein, Joyce Obradovoich, Alfred Legendre, Tara Haddad, Kevin Hahn, Barbara E. Powers & Darren Warren. (2008) Doxorubicin and BAY 12–9566 for the Treatment of Osteosarcoma in Dogs: A Randomized, Double‐Blind, Placebo‐Controlled Study. Journal of Veterinary Internal Medicine 21:4, pages 783-790.
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Hyun‐Guy Kang, Han‐Soo Kim, Kap‐Jung Kim, Joo Han Oh, Mi‐Ra Lee, So Mi Seol & Ilkyu Han. (2007) RECK expression in osteosarcoma: correlation with matrix metalloproteinases activation and tumor invasiveness. Journal of Orthopaedic Research 25:5, pages 696-702.
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Philipp Henle, Gerald Zimmermann & Stefan Weiss. (2005) Matrix metalloproteinases and failed fracture healing. Bone 37:6, pages 791-798.
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Kristin Bjørnland, Kjersti Flatmark, Solveig Pettersen, Ansgar O. Aaasen, Øystein Fodstad & Gunhild M. Mælandsmo. (2005) Matrix Metalloproteinases Participate in Osteosarcoma Invasion. Journal of Surgical Research 127:2, pages 151-156.
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