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ORIGINAL ARTICLE

Effect of hypo-, iso- and hypertonic saline irrigation on secretory mucins and morphology of cultured human nasal epithelial cells

, , , & , PhD , MD
Pages 1296-1300 | Received 04 Apr 2005, Published online: 08 Jul 2009

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Jesse Tapiala, Antti Hyvärinen, Sanna Toppila-Salmi, Eero Suihko & Elina Penttilä. (2021) Nasal saline irrigation: prescribing habits and attitudes of physicians and pharmacists. Scandinavian Journal of Primary Health Care 39:1, pages 35-43.
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Suzy Huijghebaert, Shehzad Parviz, David Rabago, Amy Baxter, Uday Chatterjee, Farhan R. Khan, Cristoforo Fabbris, Konstantinos Poulas & Stephen Hsu. (2023) Saline nasal irrigation and gargling in COVID-19: a multidisciplinary review of effects on viral load, mucosal dynamics, and patient outcomes. Frontiers in Public Health 11.
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Almas J. Vakil, Tarun Ojha, Shreya Prasad & Praveen Singh. (2021) Comparison of Hypertonic Saline with Normal Saline in Nasal Irrigation Post Endoscopic Sinus Surgery. Indian Journal of Otolaryngology and Head & Neck Surgery 74:S2, pages 1518-1522.
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Y. Wang, L. Jin, S.-X. Liu, K. Fan, M.-L. Qin & S.-Q. Yu. (2020) Role of nasal saline irrigation in the treatment of allergic rhinitis in children and adults: A systematic analysis. Allergologia et Immunopathologia 48:4, pages 360-367.
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Shaun A. Nguyen, Alkis J. Psaltis & Rodney J. Schlosser. (2014) Isotonic Saline Nasal Irrigation is an Effective Adjunctive Therapy to Intranasal Corticosteroid Spray in Allergic Rhinitis. American Journal of Rhinology & Allergy 28:4, pages 308-311.
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Yun-Hu Wang, Min-Sho Ku, Hai-Lun Sun & Ko-Huang Lue. (2014) Efficacy of nasal irrigation in the treatment of acute sinusitis in atopic children. Journal of Microbiology, Immunology and Infection 47:1, pages 63-69.
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Seon-Tae Kim. (2011) Medical Management of Chronic Rhinosinusitis. Korean Journal of Otorhinolaryngology-Head and Neck Surgery 54:11, pages 746.
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Dariusz Jurkiewicz & Piotr Rapiejko. (2011) Zastosowanie izotonicznego roztworu NaCl u chorych z ostrym zapaleniem błony śluzowej nosa i zatok przynosowych. Otolaryngologia Polska 65:1, pages 47-53.
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Piotr Rapiejko & Dariusz Jurkiewicz. (2010) Zastosowanie hipertonicznego roztworu wody morskiej u chorych po leczeniu operacyjnym nosa i zatok przynosowych. Otolaryngologia Polska 64:1, pages 20-30.
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A Ural, T Kocak Oktemer, Y Kizil, F Ileri & S Uslu. (2008) Impact of isotonic and hypertonic saline solutions on mucociliary activity in various nasal pathologies: clinical study. The Journal of Laryngology & Otology 123:5, pages 517-521.
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Hyun Jik Kim, Jeung‐Gweon Lee, Ju Wan Kang, Hyung‐Ju Cho, Hyun Su Kim, Hyung Kwon Byeon & Joo‐Heon Yoon. (2009) Effects of a Low Concentration Hypochlorous Acid Nasal Irrigation Solution on Bacteria, Fungi, and Virus. The Laryngoscope 118:10, pages 1862-1867.
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Hua-bin Li, Jian-bo Shi, Fang Cao, Lei Cheng, Wei-ping Wen & Geng Xu. (2008) Hypertonic saline solution stimulated CLC-3 production in primary cultured human nasal epithelial cells. Auris Nasus Larynx 35:1, pages 47-51.
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Maria T. Ventura, Olga Toungoussova, Maria P. Foschino Barbaro, Onofrio Resta, Giovanna E. Carpagnano, Silvano Dragonieri, Giovanni B. Migliori, Margherita Neri & Antonio Spanevello. (2007) Validity and reproducibility of morphologic analysis of nasal secretions obtained using ultrasonic nebulization of hypertonic solution. Annals of Allergy, Asthma & Immunology 99:3, pages 232-235.
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