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ORIGINAL ARTICLE

Therapeutic effectiveness over time of intratympanic dexamethasone as salvage treatment of sudden deafness

, PhD , MD, , , &
Pages 128-131 | Received 27 Feb 2007, Published online: 08 Jul 2009

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Read on this site (3)

Seong-Cheon Bae, He-Il Noh, Beom-Cho Jun, Eun-Ju Jeon, Jae-Hyun Seo, So-Young Park, Jun-Kyu Kim, Dong-Hee Lee, Jeong-Hoon Oh, Shi-Nae Park & Sang-Won Yeo. (2013) Efficacy of intratympanic steroid therapy for idiopathic sudden sensorineural hearing loss: comparison with systemic steroid therapy and combined therapy. Acta Oto-Laryngologica 133:5, pages 428-433.
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Roberto Filipo, Edoardo Covelli, Giorgio Balsamo & Giuseppe Attanasio. (2010) Intratympanic prednisolone therapy for sudden sensorineural hearing loss: A new protocol. Acta Oto-Laryngologica 130:11, pages 1209-1213.
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Chuan-Yi Lin, Chia-Hao Chang, Chen-Jung Chang, Jenq-Yuh Ko, Szu-Yuan Wu & Po-Hsiu Kuo. Salvage therapy for refractory sudden sensorineural hearing loss (RSSNHL): a systematic review and network meta-analysis. International Journal of Audiology 0:0, pages 1-10.
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Articles from other publishers (40)

Sichao Liang, Yunshuo Li, Zhenping Guo, Manlin Lu, Xin Li, Jia Xu, Wenjing Chen, Juanjuan Gao & Haijin Yi. (2024) Modified intratympanic steroid therapy for sudden sensorineural hearing loss via tympanic tube and gelfoam as a salvage treatment. Journal of Otology 19:1, pages 19-23.
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Pushkar Lele & Rushika Patel. (2023) Intra-Tympanic Dexamethasone Therapy via Grommet Insertion for Improved Auditory Outcome in Sudden Sensorineural Hearing Loss. Indian Journal of Otolaryngology and Head & Neck Surgery 75:S1, pages 357-362.
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Marjan Mirsalehi, Mahsa Ghajarzadeh, Mohammad Farhadi, Zeinab Akbarnejad, Sayedali Ahmadi & Mohammad Mahdi Salem. (2022) Intratympanic corticosteroid injection as a first-line treatment of the patients with idiopathic sudden sensorineural hearing loss compared to systemic steroid: A systematic review and meta-analysis. American Journal of Otolaryngology 43:5, pages 103505.
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Gina Na, Ki-Won Kim, Keun-Woo Jung, Jimin Yun, Taek-Yoon Cheong & Jeon-Mi Lee. (2022) Delayed Recovery in Idiopathic Sudden Sensorineural Hearing Loss. Journal of Clinical Medicine 11:10, pages 2792.
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Young Ho Kim, Doh Young Lee, Dong‐Han Lee & Sohee Oh. (2021) Tympanic Membrane Perforation After Intratympanic Steroid Injection: A Systematic Review and Meta‐analysis. Otolaryngology–Head and Neck Surgery 166:2, pages 249-259.
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Louise Devantier, Henriette Edemann Callesen, Lasse Rehné Jensen, Christian Mirian & Therese Ovesen. (2022) Intratympanic corticosteroid as salvage therapy in treatment of idiopathic sudden sensorineural hearing loss: A systematic review and meta-analysis. Heliyon 8:2, pages e08955.
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E.V. Garov, E.E. Garova & M.A. Pryakhina. (2022) Corticosteroids for acute sensorineural hearing loss treatment. The contemporary state of problem. Literature review. Part 1. Vestnik otorinolaringologii 87:3, pages 51.
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Ching Siong Tey, Nadja Kadom & Kavita Dedhia. (2021) Radiologic Findings in Pediatric Sudden Sensorineural Hearing Loss. Otology & Neurotology 42:8, pages 1201-1207.
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Gang Ren, Jue Xu, Longjiang Lan, Bingliang Ma & Qi Zhang. (2021) Postauricular injection of methylprednisolone sodium succinate as a salvage treatment for refractory sudden sensorineural hearing loss. Irish Journal of Medical Science (1971 -) 190:3, pages 1165-1172.
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Yeo Rim Ju, Hyoung-sik Park, Min Young Lee, Jae Yun Jung & Ji Eun Choi. (2021) Clinical Features and Hearing Outcomes of Sudden Sensorineural Hearing Loss in Diabetic Patients. Journal of Audiology and Otology 25:1, pages 27-35.
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Jin Woong Choi, Chi Kyou Lee, Sang Bin Kim, Dong Yun Lee, Sung Chul Ko, Kye Hoon Park & Seong Jun Choi. (2020) Potential benefits of salvage intratympanic dexamethasone injection in profound idiopathic sudden sensorineural hearing loss. European Archives of Oto-Rhino-Laryngology 277:8, pages 2219-2227.
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Ya Liu, Qiongqiong Chen & Yaping Xu. (2020) Research progress in refractory sudden hearing loss: steroid therapy. Journal of International Medical Research 48:1, pages 030006051988942.
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Anita Bhandari & Satish Jain. (2019) Early Intratympanic Methylprednisolone in Sudden SNHL: A Frequency-wise Analysis. Indian Journal of Otolaryngology and Head & Neck Surgery 71:3, pages 390-395.
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Sujana S. Chandrasekhar, Betty S. Tsai Do, Seth R. Schwartz, Laura J. Bontempo, Erynne A. Faucett, Sandra A. Finestone, Deena B. Hollingsworth, David M. Kelley, Steven T. Kmucha, Gul Moonis, Gayla L. Poling, J. Kirk Roberts, Robert J. Stachler, Daniel M. Zeitler, Maureen D. Corrigan, Lorraine C. Nnacheta & Lisa Satterfield. (2019) Clinical Practice Guideline: Sudden Hearing Loss (Update). Otolaryngology–Head and Neck Surgery 161:S1.
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Yixu Wang, Lin Han, Tongxiang Diao, Yuanyuan Jing, Lin Wang, Hongwei Zheng, Xin Ma, Jingcui Qi & Lisheng Yu. (2018) A comparison of systemic and local dexamethasone administration: From perilymph/cochlea concentration to cochlear distribution. Hearing Research 370, pages 1-10.
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Oak‐Sung Choo, Suk Min Yang, Hun Yi Park, Jong Bin Lee, Jeong Hun Jang, Seong Jun Choi & Yun‐Hoon Choung. (2016) Differences in clinical characteristics and prognosis of sudden low‐ and high‐frequency hearing loss. The Laryngoscope 127:8, pages 1878-1884.
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Jong Bin Lee & Seong Jun Choi. (2015) Potential Benefits of Combination Therapy as Primary Treatment for Sudden Sensorineural Hearing Loss. Otolaryngology–Head and Neck Surgery 154:2, pages 328-334.
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Nobuya Fujita, Toshiaki Yamanaka & Tadashi Kitahara. (2016) Treatment of tympanic membrane perforation with intratympanic steroid injection therapy. JOURNAL OF JAPAN SOCIETY FOR HEAD AND NECK SURGERY 25:3, pages 457-461.
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Soon Hyung Park & In Seok Moon. (2013) Round window membrane vibration may increase the effect of intratympanic dexamethasone injection. The Laryngoscope 124:6, pages 1444-1451.
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Seong J. Choi, Jong B. Lee, Hye J. Lim, Seung M. In, Jong‐Yeup Kim, Kyung H. Bae & Yun‐Hoon Choung. (2014) In Response to Intratympanic dexamethasone injection forrefractory tinnitus: Prospective placebo‐controlled study . The Laryngoscope 124:6.
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Y. Pons, A. Maffert, M. Raynal, E. Ukkola-Pons, P. Lepage & M. Kossowski. (2013) Sordera brusca. EMC - Otorrinolaringología 42:2, pages 1-9.
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Y. Pons, A. Maffert, M. Raynal, E. Ukkola-Pons, P. Lepage & M. Kossowski. (2013) Surdités brusques. EMC - Oto-rhino-laryngologie 8:1, pages 1-9.
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Sang Chul ParkKyung Jin NohYong Ju LeeSu Jin HanHyun Seung Choi. (2013) Hearing Outcome According to the Timing of Intratympanic Dexamethasone Injection in Idiopathic Sudden Sensorineural Hearing Loss. Korean Journal of Otorhinolaryngology-Head and Neck Surgery 56:1, pages 19.
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Young Ho Kim, Kyung Tae Park, Byung Yoon Choi, Min Hyun Park, Jun Ho Lee, Seung-Ha Oh & Sun O. Chang. (2011) Early combination treatment with intratympanic steroid injection in severe to profound sudden sensorineural hearing loss improves speech discrimination performance. European Archives of Oto-Rhino-Laryngology 269:10, pages 2173-2178.
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Masahiro Yamazaki, Shinji Naganawa, Hisashi Kawai, Michihiko Sone & Tsutomu Nakashima. (2012) Gadolinium distribution in cochlear perilymph: differences between intratympanic and intravenous gadolinium injection. Neuroradiology 54:10, pages 1161-1169.
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Werner Garavello, Francesca Galluzzi, Renato Maria Gaini & Diego Zanetti. (2012) Intratympanic Steroid Treatment for Sudden Deafness. Otology & Neurotology 33:5, pages 724-729.
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M. Yamazaki, S. Naganawa, M. Tagaya, H. Kawai, M. Ikeda, M. Sone, M. Teranishi, H. Suzuki & T. Nakashima. (2012) Comparison of Contrast Effect on the Cochlear Perilymph after Intratympanic and Intravenous Gadolinium Injection. American Journal of Neuroradiology 33:4, pages 773-778.
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Robert J. Stachler, Sujana S. Chandrasekhar, Sanford M. Archer, Richard M. Rosenfeld, Seth R. Schwartz, David M. Barrs, Steven R. Brown, Terry D. Fife, Peg Ford, Theodore G. Ganiats, Deena B. Hollingsworth, Christopher A. Lewandowski, Joseph J. Montano, James E. Saunders, Debara L. Tucci, Michael Valente, Barbara E. Warren, Kathleen L. Yaremchuk & Peter J. Robertson. (2012) Clinical Practice Guideline. Otolaryngology–Head and Neck Surgery 146:S3.
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Emanuele Ferri, Antonio Frisina, Anna Chiara Fasson, Enrico Armato, Giacomo Spinato & Maurizio Amadori. (2012) Intratympanic Steroid Treatment for Idiopathic Sudden Sensorineural Hearing Loss after Failure of Intravenous Therapy. ISRN Otolaryngology 2012, pages 1-6.
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Petros V. Vlastarakos, George Papacharalampous, Paul Maragoudakis, George Kampessis, Nicholas Maroudias, Dimitrios Candiloros & Thomas P. Nikolopoulos. (2011) Are intra-tympanically administered steroids effective in patients with sudden deafness? Implications for current clinical practice. European Archives of Oto-Rhino-Laryngology 269:2, pages 363-380.
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In Seok Moon, Jong Dae Lee, Jin Kim, Sung-Jong Hong & Won-Sang Lee. (2011) Intratympanic Dexamethasone Is an Effective Method as a Salvage Treatment in Refractory Sudden Hearing Loss. Otology & Neurotology 32:9, pages 1432-1436.
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Samuel A. Spear & Seth R. Schwartz. (2011) Intratympanic Steroids for Sudden Sensorineural Hearing Loss. Otolaryngology–Head and Neck Surgery 145:4, pages 534-543.
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Francesco Dispenza, Emanuele Amodio, Alessandro De Stefano, Salvatore Gallina, Donatella Marchese, Navneet Mathur & Francesco Riggio. (2011) Treatment of sudden sensorineural hearing loss with transtympanic injection of steroids as single therapy: a randomized clinical study. European Archives of Oto-Rhino-Laryngology 268:9, pages 1273-1278.
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Jae-Young Um, Chul-Ho Jang, Su-Jin Kim, Hye-Lin Kim, Seon-Young Kim, Young-Bum Cho & Seung-Heon Hong. (2011) Steroid Combination Therapy and Detoxification Enzyme Gene Polymorphisms in Sudden Sensorineural Hearing Loss Patients. Otology & Neurotology 32:5, pages 872-876.
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Jong Bin Lee, Seong Jun Choi, Keehyun Park, Hun Yi Park, Oak-Sung Choo & Yun-Hoon Choung. (2011) The efficiency of intratympanic dexamethasone injection as a sequential treatment after initial systemic steroid therapy for sudden sensorineural hearing loss. European Archives of Oto-Rhino-Laryngology 268:6, pages 833-839.
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Amy L. Rutt, Mary J. HawkshawRobert T. Sataloff. (2011) Incidence of Tympanic Membrane Perforation after Intratympanic Steroid Treatment through Myringotomy Tubes. Ear, Nose & Throat Journal 90:4, pages E21-E27.
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Yaoyao Fu, Hui Zhao, Tianyu Zhang & Fanglu Chi. (2011) Intratympanic dexamethasone as initial therapy for idiopathic sudden sensorineural hearing loss: Clinical evaluation and laboratory investigation. Auris Nasus Larynx 38:2, pages 165-171.
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Woo Seok KangYoung Ho KimKyung Ho ParkMyung-Whan SeoEun Jin SonShin Young YooJong Woo Chung. (2011) Treatment Strategy for Sudden Sensorineural Hearing Loss. Korean Journal of Otorhinolaryngology-Head and Neck Surgery 54:10, pages 675.
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Ioannis Seggas, Petros Koltsidopoulos, Athanasios Bibas, Anastasia Tzonou & Aristides Sismanis. (2011) Intratympanic Steroid Therapy for Sudden Hearing Loss. Otology & Neurotology 32:1, pages 29-35.
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Masahiro YAMAZAKI, Shinji NAGANAWA, Hisashi KAWAI, Takashi NIHASHI & Tsutomu NAKASHIMA. (2010) Signal Alteration of the Cochlear Perilymph on 3 Different Sequences after Intratympanic Gd-DTPA Administration at 3 Tesla: Comparison of 3D-FLAIR, 3D-T1-weighted Imaging, and 3D-CISS. Magnetic Resonance in Medical Sciences 9:2, pages 65-71.
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