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INNER EAR

Proapoptotic effects of NF-κB on cisplatin-induced cell death in auditory cell line

, MD, , , , &
Pages 1063-1070 | Received 23 Nov 2007, Published online: 08 Jul 2009

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Enrique R. Perez, Dana R. Libman & Thomas R. van de Water. (2012) Local drug delivery for inner ear therapy. Audiological Medicine 10:1, pages 1-20.
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Winston J. T. Tan & Srdjan M. Vlajkovic. (2023) Molecular Characteristics of Cisplatin-Induced Ototoxicity and Therapeutic Interventions. International Journal of Molecular Sciences 24:22, pages 16545.
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Peng Wu, Xianmin Wu, Chunhong Zhang, Xiaoyun Chen, Yideng Huang & He Li. (2021) Hair Cell Protection from Ototoxic Drugs. Neural Plasticity 2021, pages 1-9.
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Qing Tang, Xianren Wang, Huan Jin, Yanjun Mi, Lingfeng Liu, Mengyuan Dong, Yibing Chen & Zhengzhi Zou. (2021) Cisplatin-induced ototoxicity: Updates on molecular mechanisms and otoprotective strategies. European Journal of Pharmaceutics and Biopharmaceutics 163, pages 60-71.
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Ghazal Babolmorad, Asna Latif, Ivan K Domingo, Niall M Pollock, Cole Delyea, Aja M Rieger, W Ted Allison & Amit P Bhavsar. (2021) Toll‐like receptor 4 is activated by platinum and contributes to cisplatin‐induced ototoxicity. EMBO reports 22:5.
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Mahrous Abdelbasset Ibrahim, Ibrahim Abdelkhalek Albahlol, Farooq Ahmed Wani, Ahmed Abd-Eltawab Tammam, Mina Thabet Kelleni, Mohammed Ubaidullah Sayeed, Noha M. Abd El-Fadeal & Alaa Abdelhamid Mohamed. (2021) Resveratrol protects against cisplatin-induced ovarian and uterine toxicity in female rats by attenuating oxidative stress, inflammation and apoptosis. Chemico-Biological Interactions 338, pages 109402.
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Manas K. Mahapatra & Chandi C. Mandal. 2021. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects. Handbook of Oxidative Stress in Cancer: Therapeutic Aspects 1 28 .
Chaitanya Mamillapalli, Asmita Dhukhwa, Sandeep Sheth, Debashree Mukherjea, Leonard P. Rybak & Vickram Ramkumar. 2020. New Therapies to Prevent or Cure Auditory Disorders. New Therapies to Prevent or Cure Auditory Disorders 51 87 .
Erica Gentilin, Edi Simoni, Mariarita Candito, Diego Cazzador & Laura Astolfi. (2019) Cisplatin-Induced Ototoxicity: Updates on Molecular Targets. Trends in Molecular Medicine 25:12, pages 1123-1132.
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Mi-Jin Choi, Hyunsook Kang, Yun Yeong Lee, Oak-Sung Choo, Jeong Hun Jang, Sung-Hee Park, Jong-Seok Moon, Seong Jun Choi & Yun-Hoon Choung. (2019) Cisplatin-Induced Ototoxicity in Rats Is Driven by RIP3-Dependent Necroptosis. Cells 8:5, pages 409.
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Bernhard Englinger, Christine Pirker, Petra Heffeter, Alessio Terenzi, Christian R. Kowol, Bernhard K. Keppler & Walter Berger. (2018) Metal Drugs and the Anticancer Immune Response. Chemical Reviews 119:2, pages 1519-1624.
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Antonio F. Hernández, Aristidis M. Tsatsakis & George A. Kontadakis. 2019. Biomarkers in Toxicology. Biomarkers in Toxicology 385 399 .
Robert A. Hazlitt, Jaeki Min & Jian Zuo. (2018) Progress in the Development of Preventative Drugs for Cisplatin-Induced Hearing Loss. Journal of Medicinal Chemistry 61:13, pages 5512-5524.
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Sandeep Sheth, Debashree Mukherjea, Leonard P. Rybak & Vickram Ramkumar. (2017) Mechanisms of Cisplatin-Induced Ototoxicity and Otoprotection. Frontiers in Cellular Neuroscience 11.
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Matthew Ryals, Kwang Pak, Rahul Jalota, Arwa Kurabi & Allen F. Ryan. (2017) A kinase inhibitor library screen identifies novel enzymes involved in ototoxic damage to the murine organ of Corti. PLOS ONE 12:10, pages e0186001.
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S Levano & D Bodmer. (2015) Loss of STAT1 protects hair cells from ototoxicity through modulation of STAT3, c-Jun, Akt, and autophagy factors. Cell Death & Disease 6:12, pages e2019-e2019.
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Angela Callejo, Lara Sedó-Cabezón, Ivan Juan & Jordi Llorens. (2015) Cisplatin-Induced Ototoxicity: Effects, Mechanisms and Protection Strategies. Toxics 3:3, pages 268-293.
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Sofia Waissbluth & Sam J. Daniel. (2013) Cisplatin-induced ototoxicity: Transporters playing a role in cisplatin toxicity. Hearing Research 299, pages 37-45.
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Niliksha Gunewardene. (2013) Adenosine amine congener ameliorates cisplatin-induced hearing loss. World Journal of Otorhinolaryngology 3:3, pages 100.
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Hun Yi Park, Mi Hye Lee, Sung Un Kang, Hye Sook Hwang, Keehyun Park, Yun‐Hoon Choung & Chul‐Ho Kim. (2012) Nitric oxide mediates TNF‐α–induced apoptosis in the auditory cell line. The Laryngoscope 122:10, pages 2256-2264.
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C.T. Dinh, E. Bas, S.S. Chan, J.N. Dinh, L. Vu & T.R. Van De Water. (2011) Dexamethasone treatment of tumor necrosis factor-alpha challenged organ of Corti explants activates nuclear factor kappa B signaling that induces changes in gene expression that favor hair cell survival. Neuroscience 188, pages 157-167.
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Yan-Li Niu, Wei-Juan Zhang, Ping Wu, Bin Liu, Guo-Tao Sun, Dong-Ming Yu & Jin-Bo Deng. (2010) Expression of the apoptosis-related proteins caspase-3 and NF-κB in the hippocampus of Tg2576 mice凋亡相关基因caspase-3 和NF-κB 在阿尔茨海默病Tg2576 转基因小鼠海马内的表达. Neuroscience Bulletin 26:1, pages 37-46.
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Scott M. Haake, Christine T. Dinh, Shibing Chen, Adrien A. Eshraghi & Thomas R. Van De Water. (2009) Dexamethasone protects auditory hair cells against TNFα-initiated apoptosis via activation of PI3K/Akt and NFκB signaling. Hearing Research 255:1-2, pages 22-32.
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J.C. Adams, B. Seed, N. Lu, A. Landry & R.J. Xavier. (2009) Selective activation of nuclear factor kappa B in the cochlea by sensory and inflammatory stress. Neuroscience 160:2, pages 530-539.
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Leonard P Rybak, Debashree Mukherjea, Sarvesh Jajoo & Vickram Ramkumar. (2009) Cisplatin Ototoxicity and Protection: Clinical and Experimental Studies. The Tohoku Journal of Experimental Medicine 219:3, pages 177-186.
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C.T. Dinh, S. Haake, S. Chen, K. Hoang, E. Nong, A.A. Eshraghi, T.J. Balkany & T.R. Van De Water. (2008) Dexamethasone protects organ of corti explants against tumor necrosis factor-alpha–induced loss of auditory hair cells and alters the expression levels of apoptosis-related genes. Neuroscience 157:2, pages 405-413.
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