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Original Article

Increased urinary orosomucoid excretion: a proposed marker for inflammation and endothelial dysfunction in patients with type 2 diabetes

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Pages 272-281 | Received 13 Jul 2008, Accepted 18 Sep 2008, Published online: 08 Jul 2009

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Read on this site (3)

Karl M. Brobak, Runa M. Andreassen, Toralf Melsom, Aud Høieggen, Jon V. Norvik & Marit D. Solbu. (2022) Associations of urinary orosomucoid, N-acetyl-β-D-glucosaminidase, and albumin with blood pressure and hypertension after 7 years. The Tromsø Study. Blood Pressure 31:1, pages 270-283.
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Balázs Németh, Iván Péter, Imre Boncz, Anna Jagicza, István Kiss, Ágnes Csergő, Tamás Kőszegi, Péter Kustán, Iván G Horváth & Zénó Ajtay. (2019) Urinary orosomucoid: a new marker of cardiovascular risk in psoriatic patients?. Therapeutics and Clinical Risk Management 15, pages 831-837.
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Khalid Siddiqui, Salini S Joy, Shumaila Ilias, Haya S Alzeer & Khalid Al-Rubeaan. (2018) Urinary Biomarkers Reporting Weakness and Validation Failure in Type 2 Diabetic Nephropathy: Systematic Review. Biomarkers in Medicine 12:5, pages 487-499.
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Articles from other publishers (17)

Anatoliy A. Vinogradov, Natalia V. Chebotareva, Anna E. Bugrova, Alexander G. Brzhozovskiy, Tatiana N. Krasnova, Karina Z. Nasibullina, Alexey S. Kononikhin & Sergey V. Moiseev. (2023) Study of urinary markers of different podocytopathies by proteomic analysis. Terapevticheskii arkhiv 95:6, pages 457-561.
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Merve Durmuş, Özlem Uzunlar, Hümeyra Çelik & Tuba Çandar. (2022) Does alpha-1-acid glycoprotein determine for infertility in polycystic ovary syndrome?. European Journal of Obstetrics & Gynecology and Reproductive Biology 274, pages 155-159.
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Barbara J. Ballermann, Jenny Nyström & Börje Haraldsson. (2021) The Glomerular Endothelium Restricts Albumin Filtration. Frontiers in Medicine 8.
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Anna Medyńska, Joanna Chrzanowska, Katarzyna Kościelska-Kasprzak, Dorota Bartoszek, Marcelina Żabińska & Danuta Zwolińska. (2021) Alpha-1 Acid Glycoprotein and Podocin mRNA as Novel Biomarkers for Early Glomerular Injury in Obese Children. Journal of Clinical Medicine 10:18, pages 4129.
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Huabin Wang, Xinyu Bao, Yongjun Ma, Xiaoyun Shan & Caiqun Huang. (2020) Urinary orosomucoid 1 protein to creatinine ratio as a potential biomarker for early screening of kidney impairment in type‐2 diabetes patients. Nephrology 25:9, pages 667-675.
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Rabab Abdulwahab, Ayodele Alaiya, Zakia Shinwari, Abdul Allaith & Hayder Giha. (2019) LC‑MS/MS proteomic analysis revealed novel associations of 37 proteins with T2DM and notable upregulation of immunoglobulins. International Journal of Molecular Medicine.
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Balázs Szirmay, András Tárnok, Patrícia Sarlós, Nóra Szigeti, Andrea Ludány, Péter Kustán, Zoltán Horváth‐Szalai, Attila Miseta & Tamás Kőszegi. (2018) Elevated urinary orosomucoid excretion as a novel biomarker in Crohn’s disease. European Journal of Clinical Investigation 49:3.
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Péter Kustán, Balázs Szirmay, Tamás Kőszegi, Andrea Ludány, Gábor L. Kovács, Attila Miseta, Diána Mühl, Balázs Németh, István Kiss, Ádám Németh, Sándor Szabados & Zénó Ajtay. (2017) Monitoring urinary orosomucoid in patients undergoing cardiac surgery: A promising novel inflammatory marker. Clinical Biochemistry 50:18, pages 1002-1006.
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Péter Kustán, Balázs Szirmay, Zoltán Horváth-Szalai, Andrea Ludány, Gábor L. Kovács, Attila Miseta, Tamás Kőszegi & Diána Mühl. (2017) Urinary orosomucoid: a novel, early biomarker of sepsis with promising diagnostic performance. Clinical Chemistry and Laboratory Medicine (CCLM) 55:2, pages 299-307.
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Petra Kaplan, Bojan Vrtovec & Borut Jug. (2016) Orosomucoid is an independent predictor of prognosis in chronic heart failure. Wiener klinische Wochenschrift 128:23-24, pages 870-874.
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Li-na Hou, Fei Li, Qing-chun Zeng, Liang Su, Ping-an Chen, Zhi-hao Xu, Din-ji Zhu, Chang-hua Liu & Ding-li Xu. (2014) Excretion of Urinary Orosomucoid 1 Protein Is Elevated in Patients with Chronic Heart Failure. PLoS ONE 9:9, pages e107550.
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Mohsen Nafar, Shiva Kalantari, Shiva Samavat, Mostafa Rezaei-Tavirani, Dorothea Rutishuser & Roman A. Zubarev. (2014) The Novel Diagnostic Biomarkers for Focal Segmental Glomerulosclerosis. International Journal of Nephrology 2014, pages 1-10.
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Mathilde Svendstrup, Merete Skovdal Christiansen, Erik Magid, Eva Hommel & Bo Feldt-Rasmussen. (2013) Increased orosomucoid in urine is an independent predictor of cardiovascular and all-cause mortality in patients with type 2 diabetes at 10years of follow-up. Journal of Diabetes and its Complications 27:6, pages 570-575.
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Kentaro Inoue, Jun Wada, Jun Eguchi, Atsuko Nakatsuka, Sanae Teshigawara, Kazutoshi Murakami, Daisuke Ogawa, Takahiro Terami, Akihiro Katayama, Atsuhito Tone, Izumi Iseda, Kazuyuki Hida, Masao Yamada, Tomohisa Ogawa & Hirofumi Makino. (2013) Urinary Fetuin-A Is a Novel Marker for Diabetic Nephropathy in Type 2 Diabetes Identified by Lectin Microarray. PLoS ONE 8:10, pages e77118.
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M.S. Christiansen, D. Hesse, P. Ekbom, U. Hesse, P. Damm, E. Hommel, B. Feldt-Rasmussen & E. Mathiesen. (2010) Increased urinary orosomucoid excretion predicts preeclampsia in pregnant women with pregestational type 1 diabetes. Diabetes Research and Clinical Practice 89:1, pages 16-21.
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Agnès Matheson, Mark D. P. Willcox, Judith Flanagan & Bradley J. Walsh. (2010) Urinary biomarkers involved in type 2 diabetes: a review. Diabetes/Metabolism Research and Reviews 26:3, pages 150-171.
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David Gozal, Saeed Jortani, Ayelet B. Snow, Leila Kheirandish-Gozal, Rakesh Bhattacharjee, Jinkwan Kim & Oscar Sans Capdevila. (2009) Two-Dimensional Differential In-Gel Electrophoresis Proteomic Approaches Reveal Urine Candidate Biomarkers in Pediatric Obstructive Sleep Apnea. American Journal of Respiratory and Critical Care Medicine 180:12, pages 1253-1261.
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