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Original Article

Inhibition of Pancreatic Glucagon Release by Somatostatin: In Vitro

Pages 125-129 | Received 23 Nov 1973, Accepted 10 Jan 1974, Published online: 28 Aug 2009

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Santhosh Kumar Nagarajan, Sathya Babu, Honglae Sohn, Panneer Devaraju & Thirumurthy Madhavan. (2019) Toward a better understanding of the interaction between somatostatin receptor 2 and its ligands: a structural characterization study using molecular dynamics and conceptual density functional theory. Journal of Biomolecular Structure and Dynamics 37:12, pages 3081-3102.
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Ved V. Gossain & David R. Rovner. (1982) Pancreatic glucagon. Postgraduate Medicine 72:1, pages 87-96.
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Kjeld Hermansen, Stig Engkjær Christensen & Hans Ørskov. (1979) Characterization of somatostatin release from the pancreas: the role of potassium. Scandinavian Journal of Clinical and Laboratory Investigation 39:8, pages 717-722.
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Georg Herbai, Sighild Westman-Naeser, Lars Carlsson & Klas Nilsson. (1978) Prolonged Serum Insulin Decreasing Effects of Two Synthetic Somatostatin Analogues Studied in vivo by a New Animal Method. Upsala Journal of Medical Sciences 83:3, pages 141-144.
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L. E. Hanssen, K. F. Hanssen & J. Myren. (1977) Inhibition of Secretin Release and Pancreatic Bicarbonate Secretion by Somatostatin Infusion in Man. Scandinavian Journal of Gastroenterology 12:4, pages 391-394.
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AA. Prange Hansen, S. Engkjar Christensen & K. Lundbak. (1975) The Effect of Somatostatin on the Rise of Growth Hormone and Glucagon Secretion Induced by Arginine and L-Dopa in Diabetic Patients. Scandinavian Journal of Clinical and Laboratory Investigation 35:3, pages 205-210.
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S. E. Christensen, AA. P. Hansen, J. Iversen, K. Lundbæk, H. Örskov & K. Seyer-Hansen. (1974) Somatostatin as a Tool in Studies of Basal Carbohydrate and Lipid Metabolism in Man: Modifications of Glucagon and Insulin Release. Scandinavian Journal of Clinical and Laboratory Investigation 34:4, pages 321-325.
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Articles from other publishers (60)

Santhosh Kumar Nagarajan, Sathya Babu, Honglae Sohn & Thirumurthy Madhavan. (2020) Molecular-Level Understanding of the Somatostatin Receptor 1 (SSTR1)–Ligand Binding: A Structural Biology Study Based on Computational Methods. ACS Omega 5:33, pages 21145-21161.
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Jaideep J. Pandit, Harriet Wordsworth, Evelyn Little, Federico Formenti & Peter A. Robbins. 2014. The Central Nervous System Control of Respiration. The Central Nervous System Control of Respiration 331 340 .
David A. Jacobson, Barton L. Wicksteed & Louis H. Philipson. (2009) The α-Cell Conundrum: ATP-Sensitive K+ Channels and Glucose Sensing. Diabetes 58:2, pages 304-306.
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Charlotta S. Olofsson, Albert Salehi, Sven O. Göpel, Cecilia Holm & Patrik Rorsman. (2004) Palmitate Stimulation of Glucagon Secretion in Mouse Pancreatic α-Cells Results From Activation of l -Type Calcium Channels and Elevation of Cytoplasmic Calcium . Diabetes 53:11, pages 2836-2843.
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Roberto Baldelli, Claudia Battista, Frida Leonetti, Maria‐Rosaria Ghiggi, Maria‐Cristina Ribaudo, Antonella Paoloni, Eugenio D’Amico, Elisabetta Ferretti, Roberto Baratta, Antonio Liuzzi, Vincenzo Trischitta & Guido Tamburrano. (2003) Glucose homeostasis in acromegaly: effects of long‐acting somatostatin analogues treatment. Clinical Endocrinology 59:4, pages 492-499.
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Lars Neisig Møller, Carsten Enggaard Stidsen, Bolette Hartmann & Jens Juul Holst. (2003) Somatostatin receptors. Biochimica et Biophysica Acta (BBA) - Biomembranes 1616:1, pages 1-84.
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Robert L. Dobbins, Stephen N. Davis, Doss Neal, Andrea Caumo, Claudio Cobelli & Alan D. Cherrington. (1998) Rates of glucagon activation and deactivation of hepatic glucose production in conscious dogs. Metabolism 47:2, pages 135-142.
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Daniele Bani, Giancarlo Biliotti & Tatiana Bani Sacchi. (1991) Morphological changes in the human endocrine pancreas induced by chronic excess of endogenous glucagon. Virchows Archiv B Cell Pathology Including Molecular Pathology 60:1, pages 199-206.
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Mark A. Sheridan, Erika M. Plisetskaya, Howard A. Bern & Aubrey Gorbman. (1987) Effects of somatostatin-25 and urotensin II on lipid and carbohydrate metabolism of coho salmon, Oncorhynchus kisutch. General and Comparative Endocrinology 66:3, pages 405-414.
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Mark A. Sheridan & Howard A. Bern. (1986) Both somatostatin and the caudal neuropeptide, urotensin II, stimulate lipid mobilization from coho salmon liver incubated in vitro. Regulatory Peptides 14:4, pages 333-344.
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Lennart Boquist & Stefan O. Emdin. 1985. The Diabetic Pancreas. The Diabetic Pancreas 127 169 .
Bruno W. Volk & Klaus F. Wellmann. 1985. The Diabetic Pancreas. The Diabetic Pancreas 117 125 .
Bruno W. Volk & Klaus F. Wellmann. 1985. The Diabetic Pancreas. The Diabetic Pancreas 265 273 .
J.A.H. Wass. (1983) Growth hormone neuroregulation and the clinical relevance of somatostatin. Clinics in Endocrinology and Metabolism 12:3, pages 695-724.
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E. Samols, G. C. Weir & S. Bonner-Weir. 1983. Glucagon II. Glucagon II 133 173 .
J.A.H. Wass. 1982. Clinical Neuroendocrinology. Clinical Neuroendocrinology 359 395 .
S. EFENDIĆ & R. LUFT. 1981. The Islets of Langerhans. The Islets of Langerhans 257 273 .
J.Wayne Leitner, Robert M. Rifkin, Arie Maman & Karl E. Sussman. (1980) The relationship between somatostatin binding and cyclic AMP-stimulated protein kinase inhibition. Metabolism 29:11, pages 1065-1074.
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A. V. Greco, L. Altomonte, G. Ghirlanda, A. G. Rebuzzi, R. Manna & A. Bertoli. (1980) Somatostatin infusion in liver cirrhosis: Glucagon control of glucose homeostasis. Diabetologia 18:3, pages 187-191.
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J. Iversen & K. Hermansen. (1980) Characterization of the inhibitory effect of somatostatin upon insulin and glucagon release in the isolated perfused canine pancreas: Evidence for interaction with calcium. Metabolism 29:2, pages 151-160.
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Michael Briggs & Alan CorbinJ. E. Gerich. 1980. Progress in Hormone Biochemistry and Pharmacology. Progress in Hormone Biochemistry and Pharmacology 55 147 .
Kjeld Hermansen & Thue W. Schwartz. (1979) Differential sensitivity to somatostatin of pancreatic polypeptide, glucagon and insulin secretion from the isolated perfused canine pancreas. Metabolism 28:12, pages 1229-1233.
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K. Hermansen, H. �rskov & S. E. Christensen. (1979) Streptozotocin diabetes: A glucoreceptor dysfunction affecting D cells as well as B and A cells. Diabetologia 17:6, pages 385-389.
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K. Hermansen, S. E. Christensen & H. �rskov. (1979) Characterisation of somatostatin release from the pancreas. Diabetologia 16:4, pages 261-266.
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ANDREW V. SCHALLY, DAVID H. COY, CHESTER A. MEYERS & ABBA J. KASTIN. 1979. Hypothalamic Hormones. Hypothalamic Hormones 1 54 .
M. J. GalvinJrJr & A. M. Lefer. (1979) Effect of suppression of endocrine or exocrine pancreatic function in hemorrhagic shock. Experientia 35:1, pages 55-57.
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Akio Kaneto, Hiroshi Kajinuma, Toshio Kaneko & Kinori Kosaka. (1978) Effect of phentolamine on the somatostatin-induced inhibition of glucagon and insulin secretion. Metabolism 27:8, pages 901-910.
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C McIntosh, R Arnold, E Bothe, H Becker, J Kobberling & W Creutzfeldt. (1978) Gastrointestinal somatostatin: extraction and radioimmunoassay in different species.. Gut 19:7, pages 655-663.
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T. E. Adrian, S. R. Bloom, K. Hermansen & J. Iversen. (1978) Pancreatic polypeptide, glucagon and insulin secretion from the isolated perfused canine pancreas. Diabetologia 14:6, pages 413-417.
Crossref
SUAD EFENDIĆ, TOMAS HÖKFELT & ROLF LUFT. 1978. Including International Studies in the Epidemiology of Diabetes. Including International Studies in the Epidemiology of Diabetes 367 424 .
K. Becker, U. Wendel, H. Przyrembel, M. Tsotsalas, H. M�ntefering & H. J. Bremer. (1978) Beta cell nesidioblastosis. European Journal of Pediatrics 127:2, pages 75-89.
Crossref
A. V. Schally, D. H. Coy, A. Arimura, T. W. Redding, A. J. Kastin, C. Meyers, J. Seprodi, R. Chang, W.-Y. Huang, K. Chihara, E. Pedroza, J. Vilchez & R. Millar. 1978. Pharmacology of the Hypothalamus. Pharmacology of the Hypothalamus 161 206 .
K. G. M. M. ALBERTI & M. NATTRASS. (2008) The physiological function of glucagon. European Journal of Clinical Investigation 7:3, pages 151-154.
Crossref
Antonio Gomez-Pan & Reginald Hall. (1977) Somatostatin (Growth hormone-release inhibiting hormone). Clinics in Endocrinology and Metabolism 6:1, pages 181-200.
Crossref
C. I. A. BLAUTH, P. H. SÖNKSEN, C. V. TOMPKINS & S. R. BLOOM. (2008) THE HYPOGLYCAEMIC ACTION OF SOMATOSTATIN IN THE ANAESTHETIZED DOG. Clinical Endocrinology 6:1, pages 17-25.
Crossref
Andrew V. Schally & Akira Arimura. 1977. Clinical Neuroendocrinology. Clinical Neuroendocrinology 1 42 .
A. J. Aasen, D. P. Chakraborty, C. R. Enzell, D. Gross, J. Jacob, K. H. Overton, D. J. Picken, A. R. Pinder, W. Voelter & I. WahlbergW. Voelter. 1977. Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products. Fortschritte der Chemie Organischer Naturstoffe / Progress in the Chemistry of Organic Natural Products 439 564 .
K. Lundbaek. 1977. Diabetes mellitus • B. Diabetes mellitus • B 175 187 .
Lennart Boquist. 1977. The Diabetic Pancreas. The Diabetic Pancreas 129 169 .
Bruno W. Volk & Klaus F. Wellmann. 1977. The Diabetic Pancreas. The Diabetic Pancreas 121 128 .
Bruno W. Volk & Klaus F. Wellmann. 1977. The Diabetic Pancreas. The Diabetic Pancreas 261 269 .
A. Kaneto. 1977. GLUCAGON: Its Role in Physiology and Clinical Medicine. GLUCAGON: Its Role in Physiology and Clinical Medicine 271 286 .
Ellis Samols & J. Harrison. (1976) Remarkable potency of somatostatin as a glucagon suppressant. Metabolism 25:11, pages 1495-1497.
Crossref
C. Lucke, H. J. Mitzkat & A. M�hlen. (1976) SomatostatinSomatostatin-A Review. Klinische Wochenschrift 54:7, pages 293-301.
Crossref
K. Lundbaek, AaP. Hansen, H. Ørskov, S.E. Christensen, J. Iversen, K. Seyer-Hansen, K.G.M.M. Alberti, R. Whitefoot, K.G.M.M. Alberti & R. Whitefoot. (1976) FAILURE OF SOMATOSTATIN TO CORRECT MANIFEST DIABETIC KETOACIDOSIS. The Lancet 307:7953, pages 215-218.
Crossref
ALLEN W. ROOT, EDWARD O. REITER & YOSEF WEISMAN. (1976) Current Status and Clinical Application of the Hypothalamic Hormones. Advances in Pediatrics 23:1, pages 151-211.
Crossref
Reginald Hall & Antonio Gomez-Pan. 1976. Advances in Clinical Chemistry Volume 18. Advances in Clinical Chemistry Volume 18 173 212 .
Roger H. Unger. 1977. The Year in Metabolism 1975–1976. The Year in Metabolism 1975–1976 73 111 .
John E. Gerich. 1976. Hypothalamus and Endocrine Functions. Hypothalamus and Endocrine Functions 127 143 .
J. R. Tata. 1976. Ciba Foundation Symposium 41 ‐ Polypeptide Hormones: Molecular and Cellular Aspects. Ciba Foundation Symposium 41 ‐ Polypeptide Hormones: Molecular and Cellular Aspects 297 369 .
Niels Juel Christensen, Stig Engkjœr Christensen, Aage Prange Hansen & Knud Lundbœk. (1975) The effect of somatostatin on plasma noradrenaline and plasma adrenaline concentrations during exercise and hypoglycemia. Metabolism 24:11, pages 1267-1272.
Crossref
Patrick Robberecht, Monique Deschodt-Lanckman, Philippe De Neef & Jean Christophe. (1975) Effects of somatostatin on pancreatic exocrine function. Interaction with secretin. Biochemical and Biophysical Research Communications 67:1, pages 315-323.
Crossref
C. Rufener, M. P. Dubois, F. Malaisse-Lagae & L. Orci. (1975) Immuno-fluorescent reactivity to anti-somatostatin in the gastro-intestinal mucosa of the dog. Diabetologia 11:4, pages 321-324.
Crossref
. (1975) Somatostatin and Diabetes. The Lancet 305:7920, pages 1323-1324.
Crossref
. (1975) Addendum. The Lancet 305:7920, pages 1311.
Crossref
A. Gomez-Pan, M. Albinus, J.D. Reed, B. Shaw, R. Hall, G.M. Besser, D.H. Coy, A.J. Kastin & A.V. Schally. (1975) DIRECT INHIBITION OF GASTRIC ACID AND PEPSIN SECRETION BY GROWTH-HORMONE RELEASE-INHIBITING HORMONE IN CATS. The Lancet 305:7912, pages 888-890.
Crossref
WYLIE VALE, PAUL BRAZEAU, CATHERINE RIVIER, MARVIN BROWN, BARBARA BOSS, JEAN RIVIER, ROGER BURGUS, NICHOLAS LING & ROGER GUILLEMIN. 1975. Proceedings of the 1974 Laurentian Hormone Conference. Proceedings of the 1974 Laurentian Hormone Conference 365 397 .
S.S.C. YEN, B.L. LASLEY, C.F. WANG, H. LEBLANC & T.M. SILER. 1975. Proceedings of the 1974 Laurentian Hormone Conference. Proceedings of the 1974 Laurentian Hormone Conference 321 363 .
Wilfred Y. Fujimoto, John W. Ensinck & Robert H. Williams. (1974) Somatostatin inhibits insulin and glucagon release by monolayer cell cultures of rat endocrine pancreas. Life Sciences 15:11, pages 1999-2004.
Crossref
S.R Bloom, C.H Mortimer, M.O Thorner, G.M Besser, R Hall, A Gomez-Pan, V.M Roy, R.C.G Russell, D.H Coy, A.T Kastin & A.V Schally. (1974) INHIBITION OF GASTRIN AND GASTRIC-ACID SECRETION BY GROWTH-HORMONE RELEASE-INHIBITING HORMONE. The Lancet 304:7889, pages 1106-1109.
Crossref

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