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Research Article

Absence of Dysfunctional Ileal Sodium?Bile Acid Cotransporter Gene Mutations in Patients with Adult-Onset Idiopathic Bile Acid Malabsorption

Pages 1077-1080 | Published online: 08 Jul 2009

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Michael Camilleri. (2014) Advances in understanding of bile acid diarrhea. Expert Review of Gastroenterology & Hepatology 8:1, pages 49-61.
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Julian RF Walters. (2010) Defining primary bile acid diarrhea: making the diagnosis and recognizing the disorder. Expert Review of Gastroenterology & Hepatology 4:5, pages 561-567.
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Antal Bajor, Per-Göran Gillberg & Hasse Abrahamsson. (2010) Bile acids: short and long term effects in the intestine. Scandinavian Journal of Gastroenterology 45:6, pages 645-664.
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Tohru SAEKI, Satoko MIZUSHIMA, Kazumitsu UEDA, Kimikazu IWAMI & Ryuhei KANAMOTO. (2009) Mutational Analysis of Uncharged Polar Residues and Proline in the Distal One-Third (Thr130–Pro142) of the Highly Conserved Region of Mouse Slc10a2. Bioscience, Biotechnology, and Biochemistry 73:7, pages 1535-1540.
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Articles from other publishers (59)

Michael Camilleri & Samuel Nurko. (2021) Bile Acid Diarrhea in Adults and Adolescents. Neurogastroenterology & Motility 34:4.
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Stephen J. Keely, Andreacarola Urso, Alexandr V. Ilyaskin, Christoph Korbmacher, Nigel W. Bunnett, Daniel P. Poole & Simona E. Carbone. (2022) Contributions of bile acids to gastrointestinal physiology as receptor agonists and modifiers of ion channels. American Journal of Physiology-Gastrointestinal and Liver Physiology 322:2, pages G201-G222.
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Małgorzata Bednarska-Makaruk & Agnieszka Ługowska. 2022. Cholesterol. Cholesterol 553 607 .
Caroline Gee, Catherine Fleuret, Ana Wilson, Daniel Levine, Ramy Elhusseiny, Ann Muls, David Cunningham & Darina Kohoutova. (2021) Bile Acid Malabsorption as a Consequence of Cancer Treatment: Prevalence and Management in the National Leading Centre. Cancers 13:24, pages 6213.
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Michael CamilleriPriya Vijayvargiya. (2020) The Role of Bile Acids in Chronic Diarrhea. American Journal of Gastroenterology 115:10, pages 1596-1603.
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Priya Vijayvargiya & Michael Camilleri. (2019) Current Practice in the Diagnosis of Bile Acid Diarrhea. Gastroenterology 156:5, pages 1233-1238.
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Jean-Pierre Raufman, Melissa Metry, Jessica Felton, Kunrong Cheng, Su Xu & James Polli. (2018) A 19F magnetic resonance imaging-based diagnostic test for bile acid diarrhea. Magnetic Resonance Materials in Physics, Biology and Medicine 32:1, pages 163-171.
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Rui-gang HouLei FanJun-jin LiuYao ChengZhuang-peng ChangBei WuYun-yun Shao. (2018) Bile acid malabsorption is associated with diarrhea in acute phase of colitis. Canadian Journal of Physiology and Pharmacology 96:12, pages 1328-1336.
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Bernardo Fani, Lorenzo Bertani, Italia Paglianiti, Lorenzo Fantechi, Nicola De Bortoli, Francesco Costa, Duccio Volterrani, Santino Marchi & Massimo Bellini. (2018) Pros and Cons of the SeHCAT Test in Bile Acid Diarrhea: A More Appropriate Use of an Old Nuclear Medicine Technique. Gastroenterology Research and Practice 2018, pages 1-9.
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Paula R. Giaretta, Raquel R. Rech, Blake C. Guard, Amanda B. Blake, Anna K. Blick, Jörg M. Steiner, Jonathan A. Lidbury, Audrey K. Cook, Mohsen Hanifeh, Thomas Spillmann, Susanne Kilpinen, Pernilla Syrjä & Jan S. Suchodolski. (2018) Comparison of intestinal expression of the apical sodium-dependent bile acid transporter between dogs with and without chronic inflammatory enteropathy. Journal of Veterinary Internal Medicine 32:6, pages 1918-1926.
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Kunrong Cheng, Melissa Metry, Jessica Felton, Aaron C. Shang, Cinthia B. Drachenberg, Su Xu, Min Zhan, Justin Schumacher, Grace L. Guo, James E. Polli & Jean-Pierre Raufman. (2018) Diminished gallbladder filling, increased fecal bile acids, and promotion of colon epithelial cell proliferation and neoplasia in fibroblast growth factor 15-deficient mice. Oncotarget 9:39, pages 25572-25585.
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Jessica M. Lee, Jessica R. Ong, Laurent Vergnes, Thomas Q. de Aguiar Vallim, Jonathan Nolan, Rita M. Cantor, JulianR.F. Walters & Karen Reue. (2018) Diet1, bile acid diarrhea, and FGF15/19: mouse model and human genetic variants. Journal of Lipid Research 59:3, pages 429-438.
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C. Borup, S. Wildt, J. J. Rumessen, P. N. Bouchelouche, J. Graff, M. Damgaard, C. McQuitty, D. Rainteau & L. K. Munck. (2017) Chenodeoxycholic acid stimulated fibroblast growth factor 19 response – a potential biochemical test for bile acid diarrhoea.. Alimentary Pharmacology & Therapeutics 45:11, pages 1433-1442.
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Hongtao Liu, Guoxun Pang, Jinfeng Ren, Yue Zhao & Juxian Wang. (2017) A novel class of apical sodium--dependent bile salt transporter inhibitors: 1-(2,4-bifluorophenyl)-7-dialkylamino-1,8-naphthyridine-3-carboxamides. Acta Pharmaceutica Sinica B 7:2, pages 223-229.
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David Q.-H. Wang, Brent A. Neuschwander-Tetri & Piero Portincasa. (2016) The Biliary System, Second Edition. Colloquium Series on Integrated Systems Physiology: From Molecule to Function 8:5, pages i-178.
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N. Mottacki, M. Simrén & A. Bajor. (2016) Review article: bile acid diarrhoea - pathogenesis, diagnosis and management. Alimentary Pharmacology & Therapeutics 43:8, pages 884-898.
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Michael Camilleri. (2016) Editorial: Dissecting Molecular Mechanisms in Bile Acid Diarrhea. American Journal of Gastroenterology 111:3, pages 433-435.
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Michael Camilleri & Alexander C. Ford. 2017. Gastrointestinal Pharmacology. Gastrointestinal Pharmacology 75 113 .
Michael Camilleri, Paula Carlson, Andres Acosta & Irene Busciglio. (2015) Colonic mucosal gene expression and genotype in irritable bowel syndrome patients with normal or elevated fecal bile acid excretion. American Journal of Physiology-Gastrointestinal and Liver Physiology 309:1, pages G10-G20.
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Michael Camilleri. (2015) Bile Acid Diarrhea: Prevalence, Pathogenesis, and Therapy. Gut and Liver 9:3.
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F. Gothe, F. Beigel, C. Rust, M. Hajji, S. Koletzko & F. Freudenberg. (2014) Bile acid malabsorption assessed by 7 alpha-hydroxy-4-cholesten-3-one in pediatric inflammatory bowel disease: Correlation to clinical and laboratory findings. Journal of Crohn's and Colitis 8:9, pages 1072-1078.
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Richard N. Appleby & Julian R. F. Walters. (2014) The role of bile acids in functional GI disorders. Neurogastroenterology & Motility 26:8, pages 1057-1069.
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Julian R. F. Walters. (2014) Bile acid diarrhoea and FGF19: new views on diagnosis, pathogenesis and therapy. Nature Reviews Gastroenterology & Hepatology 11:7, pages 426-434.
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Michael Camilleri, Paula Carlson, Andres Acosta, Irene Busciglio, Asha A. Nair, Simon J. Gibbons, Gianrico Farrugia & Eric W. Klee. (2014) RNA sequencing shows transcriptomic changes in rectosigmoid mucosa in patients with irritable bowel syndrome-diarrhea: a pilot case-control study. American Journal of Physiology-Gastrointestinal and Liver Physiology 306:12, pages G1089-G1098.
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Ralf Kubitz, Carola Dröge, Stefanie Kluge, Jan Stindt & Dieter Häussinger. (2014) Genetic variations of bile salt transporters. Drug Discovery Today: Technologies 12, pages e55-e67.
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Diana Vivian, Kunrong Cheng, Sandeep Khurana, Su Xu, Edwin H. Kriel, Paul A. Dawson, Jean-Pierre Raufman & James E. Polli. (2014) In Vivo Performance of a Novel Fluorinated Magnetic Resonance Imaging Agent for Functional Analysis of Bile Acid Transport . Molecular Pharmaceutics 11:5, pages 1575-1582.
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Michael Camilleri, Eric W. Klee, Andrea Shin, Paula Carlson, Ying Li, Madhusudan Grover & Alan R. Zinsmeister. (2014) Irritable bowel syndrome-diarrhea: characterization of genotype by exome sequencing, and phenotypes of bile acid synthesis and colonic transit. American Journal of Physiology-Gastrointestinal and Liver Physiology 306:1, pages G13-G26.
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Diana Vivian, Kunrong Cheng, Sandeep Khurana, Su Xu, Valerie Whiterock, Drew Witter, Kimberley A. Lentz, Kenneth S. Santone, Jean-Pierre Raufman & James E. Polli. (2013) Design and Characterization of a Novel Fluorinated Magnetic Resonance Imaging Agent for Functional Analysis of Bile Acid Transporter Activity. Pharmaceutical Research 30:5, pages 1240-1251.
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P.-O. Stotzer, H. Abrahamsson, A. Bajor & R. Sadik. (2013) Effect of Cholestyramine on Gastrointestinal Transit in Patients with Idiopathic Bile Acid Diarrhea: A Prospective, Open-Label Study. Neuroenterology 2, pages 1-5.
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Michael Camilleri. (2012) Peripheral Mechanisms in Irritable Bowel Syndrome. New England Journal of Medicine 367:17, pages 1626-1635.
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Banny S. Wong, Michael Camilleri, Paula Carlson, Sanna McKinzie, Irene Busciglio, Olga Bondar, Roy B. Dyer, Jesse Lamsam & Alan R. Zinsmeister. (2012) Increased Bile Acid Biosynthesis Is Associated With Irritable Bowel Syndrome With Diarrhea. Clinical Gastroenterology and Hepatology 10:9, pages 1009-1015.e3.
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David Q.-H. Wang, Brent A. Neuschwander-Tetri & Piero Portincasa. (2012) The Biliary System. Colloquium Series on Integrated Systems Physiology: From Molecule to Function 4:2, pages 1-148.
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Barbara Döring, Thomas Lütteke, Joachim Geyer & Ernst Petzinger. 2012. Co-Transport Systems. Co-Transport Systems 105 168 .
Paul A. Dawson. 2012. Physiology of the Gastrointestinal Tract. Physiology of the Gastrointestinal Tract 1461 1484 .
Richard H Ho, Brenda F Leake, Brad L Urquhart, Jamie C Gregor, Paul A Dawson & Richard B Kim. (2011) Functional characterization of genetic variants in the apical sodium-dependent bile acid transporter (ASBT; SLC10A2). Journal of Gastroenterology and Hepatology 26:12, pages 1740-1748.
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Ian Johnston, Jonathan Nolan, Sanjeev S. Pattni & Julian R. F. Walters. (2011) New Insights into Bile Acid Malabsorption. Current Gastroenterology Reports 13:5, pages 418-425.
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Banny S. Wong, Michael Camilleri, Paula J. Carlson, Maria E. Guicciardi, Duane Burton, Sanna McKinzie, Archana S. Rao, Alan R. Zinsmeister & Gregory J. Gores. (2011) A Klothoβ Variant Mediates Protein Stability and Associates With Colon Transit in Irritable Bowel Syndrome With Diarrhea. Gastroenterology 140:7, pages 1934-1942.
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Paul A. Dawson. 2011. Drug Transporters. Drug Transporters 169 203 .
Julian R. F. WaltersSanjeev S. Pattni. (2010) Managing bile acid diarrhoea. Therapeutic Advances in Gastroenterology 3:6, pages 349-357.
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Paul A. Dawson, Tian Lan & Anuradha Rao. (2009) Bile acid transporters. Journal of Lipid Research 50:12, pages 2340-2357.
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S. Pattni & J. R. F. Walters. (2009) Recent advances in the understanding of bile acid malabsorption. British Medical Bulletin 92:1, pages 79-93.
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Alan F. Hofmann, David J. Mangelsdorf & Steven A. Kliewer. (2009) Chronic Diarrhea Due to Excessive Bile Acid Synthesis and Not Defective Ileal Transport: A New Syndrome of Defective Fibroblast Growth Factor 19 Release. Clinical Gastroenterology and Hepatology 7:11, pages 1151-1154.
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Julian R.F. Walters, Ali M. Tasleem, Omer S. Omer, W. Gordon Brydon, Tracy Dew & Carel W. le Roux. (2009) A New Mechanism for Bile Acid Diarrhea: Defective Feedback Inhibition of Bile Acid Biosynthesis. Clinical Gastroenterology and Hepatology 7:11, pages 1189-1194.
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Olga Renner, Simone Harsch, Elke Schaeffeler, Stefan Winter, Matthias Schwab, Marcin Krawczyk, Jonas Rosendahl, Henning Wittenburg, Frank Lammert & Eduard F. Stange. (2009) A Variant of the SLC10A2 Gene Encoding the Apical Sodium-Dependent Bile Acid Transporter Is a Risk Factor for Gallstone Disease. PLoS ONE 4:10, pages e7321.
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Xiaowan ZhengSean EkinsJean-Pierre RaufmanJames E. Polli. (2009) Computational Models for Drug Inhibition of the Human Apical Sodium-Dependent Bile Acid Transporter. Molecular Pharmaceutics 6:5, pages 1591-1603.
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X. FAN & J. H. SELLIN. (2009) Review article: small intestinal bacterial overgrowth, bile acid malabsorption and gluten intolerance as possible causes of chronic watery diarrhoea. Alimentary Pharmacology & Therapeutics 29:10, pages 1069-1077.
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Olga Renner, Simone Harsch, Elke Schaeffeler, Matthias Schwab, Dietmar M. Klass, Wolfgang Kratzer & Eduard F. Stange. (2009) Mutation screening of apical sodium-dependent bile acid transporter (SLC10A2): novel haplotype block including six newly identified variants linked to reduced expression. Human Genetics 125:4, pages 381-391.
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Sara Balesaria, Robert J. Pell, Lucy J. Abbott, Ali Tasleem, Konstantia-Marie Chavele, Natalie F. Barley, Umma Khair, Alex Simon, Kieran J. Moriarty, W. Gordon Brydon & Julian R.F. Walters. (2008) Exploring possible mechanisms for primary bile acid malabsorption: evidence for different regulation of ileal bile acid transporter transcripts in chronic diarrhoea. European Journal of Gastroenterology & Hepatology 20:5, pages 413-422.
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Henrik Westergaard. (2008) Bile acid malabsorption. Current Treatment Options in Gastroenterology 10:1, pages 28-33.
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Marco Montagnani. (2006) Analysis of ileal sodium/bile acid cotransporter and related nuclear receptor genes in a family with multiple cases of idiopathic bile acid malabsorption. World Journal of Gastroenterology 12:47, pages 7710.
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