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Research Article

Transforming Growth Factor-Beta 1, Activin and Follistatin in Patients with Hepatocellular Carcinoma and Patients with Alcoholic Cirrhosis

Pages 233-238 | Published online: 08 Jul 2009

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Scott Z Fields, Shiroo Parshad, Madhurima Anne, Haralambos Raftopoulos, Mark J Alexander, Matthew L Sherman, Abderrahmane Laadem, Victoria Sung & Evangelos Terpos. (2013) Activin receptor antagonists for cancer-related anemia and bone disease. Expert Opinion on Investigational Drugs 22:1, pages 87-101.
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Matthew Hamang, Benjamin Yaden & Guoli Dai. (2023) Gastrointestinal pharmacology activins in liver health and disease. Biochemical Pharmacology 214, pages 115668.
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Jonas Santol, David Pereyra, Stefanie Haegele, Daphni Ammon, Gregor Ortmayr, Anita Pirabe, Jan Philipp Jonas, Stefan Schuster, Sarang Kim, Toni Nguyen, Thomas Gruenberger, Alice Assinger & Patrick Starlinger. (2023) The Ratio of Activin A and Follistatin-Like 3 Is Associated With Posthepatectomy Liver Failure and Morbidity in Patients Undergoing Liver Resection. Gastro Hep Advances 2:5, pages 642-651.
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Salih Boga, Abdullah Emre Yildirim, Enver Ucbilek, Ali Riza Koksal, Sevil Tokdemir Sisman, Ibrahim Durak, Ilker Sen, Beril Dogu, Erdinc Serin, Ayse Bolat Ucbilek, Makbule Ozge Yildirim, Sukru Mehmet Erturk, Huseyin Alkim & Canan Alkim. (2022) The effect of sarcopenia and serum myokines on prognosis and survival in cirrhotic patients: a multicenter cross-sectional study. European Journal of Gastroenterology & Hepatology 34:12, pages 1261-1268.
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Meenakshi Vachher, Savita Bansal, Bhupender Kumar, Sandeep Yadav, Taruna Arora, Nalini Moza Wali & Archana Burman. (2022) Contribution of organokines in the development of NAFLD/NASH associated hepatocellular carcinoma. Journal of Cellular Biochemistry 123:10, pages 1553-1584.
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Chalermrat Bunchorntavakul & K. Rajender Reddy. (2020) Review article: malnutrition/sarcopenia and frailty in patients with cirrhosis. Alimentary Pharmacology & Therapeutics 51:1, pages 64-77.
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Federico Remes Lenicov, Ana Luz Paletta, Melina Gonzalez Prinz, Augusto Varese, Clara E. Pavillet, Álvaro Lopez Malizia, Juan Sabatté, Jorge Raul Geffner & Ana Ceballos. (2018) Prostaglandin E2 Antagonizes TGF-β Actions During the Differentiation of Monocytes Into Dendritic Cells. Frontiers in Immunology 9.
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Ben Davidson. 2018. Serous Effusions. Serous Effusions 283 291 .
Anders Rasmussen Rinnov, Peter Plomgaard, Bente Klarlund Pedersen & Lise Lotte Gluud. (2016) Impaired Follistatin Secretion in Cirrhosis. The Journal of Clinical Endocrinology & Metabolism 101:9, pages 3395-3400.
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Nevine El-Abd, Amal Fawzy, Tamer Elbaz & Sherif Hamdy. (2015) Evaluation of annexin A2 and as potential biomarkers for hepatocellular carcinoma. Tumor Biology 37:1, pages 211-216.
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Lena Dreikhausen, Susanne Blank, Leila Sisic, Ulrike Heger, Wilko Weichert, Dirk Jäger, Thomas Bruckner, Natalia Giese, Lars Grenacher, Christine Falk, Katja Ott & Thomas Schmidt. (2015) Association of angiogenic factors with prognosis in esophageal cancer. BMC Cancer 15:1.
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Bassem Refaat, Ahmed Mohamed Ashshi, Adel Galal El-Shemi & Esam Azhar. (2015) Activins and Follistatin in Chronic Hepatitis C and Its Treatment with Pegylated-Interferon- α Based Therapy . Mediators of Inflammation 2015, pages 1-16.
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Jin Won Yang, Tran Thi Hien, Sung Chul Lim, Dae Won Jun, Hong Seok Choi, Jung-Hoon Yoon, Il Je Cho & Keon Wook Kang. (2014) Pin1 induction in the fibrotic liver and its roles in TGF-β1 expression and Smad2/3 phosphorylation. Journal of Hepatology 60:6, pages 1235-1241.
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Amany H. Mansour, Tawfik R. Elkhoda, Rokia Saad Ayyad, Maha Ragab Habeeb & Mohammed Amin Mohammed. (2014) Regulation of Cancer Stem Cell Marker (CD133) by Transforming Growth Factor Beta in Hepatocellular Carcinoma. International Journal of Cancer Research 10:2, pages 65-73.
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Takeshi Tomoda, Kazuhiro Nouso, Koji Miyahara, Sayo Kobayashi, Hideaki Kinugasa, Junki Toyosawa, Hiroaki Hagihara, Kenji Kuwaki, Hideki Onishi, Shinichiro Nakamura, Fusao Ikeda, Yasuhiro Miyake, Hidenori Shiraha, Akinobu Takaki & Kazuhide Yamamoto. (2013) Prognotic impact of serum follistatin in patients with hepatocellular carcinoma. Journal of Gastroenterology and Hepatology 28:8, pages 1391-1396.
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Guo-Cai Li, Qing-Hai Ye, Qiong-Zhu Dong, Ning Ren, Hu-Liang Jia & Lun-Xiu Qin. (2012) TGF beta1 and related-Smads contribute to pulmonary metastasis of hepatocellular carcinoma in mice model. Journal of Experimental & Clinical Cancer Research 31:1.
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Argyro Voumvouraki, George Notas, Mairi Koulentaki, Maria Georgiadou, Stefanos Klironomos & Elias Kouroumalis. (2012) Increased serum activin‐A differentiates alcoholic from cirrhosis of other aetiologies. European Journal of Clinical Investigation 42:8, pages 815-822.
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Marion Martin & Zdenko Herceg. (2012) From hepatitis to hepatocellular carcinoma: a proposed model for cross-talk between inflammation and epigenetic mechanisms. Genome Medicine 4:1, pages 8.
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Ben Davidson. 2012. Serous Effusions. Serous Effusions 241 247 .
K Frost, K Seir, A Lackner, M Grusch, B Grasl-Kraupp, R Schulte-Hermann & C Rodgarkia-Dara. (2011) Inhibin/activin expression in human and rodent liver: subunits α and βB as new players in human hepatocellular carcinoma?. British Journal of Cancer 104:8, pages 1303-1312.
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Anuradha Menthena, Christoph I. Koehler, Jaswinderpal S. Sandhu, Mladen I. Yovchev, Ethel Hurston, David A. Shafritz & Michael Oertel. (2011) Activin A, p15INK4b Signaling, and Cell Competition Promote Stem/Progenitor Cell Repopulation of Livers in Aging Rats. Gastroenterology 140:3, pages 1009-1020.e8.
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Tereza Ventura-Holman, Abulkhair Mamoon, Maria C. Subauste & Jose S. Subauste. (2010) The effect of oncoprotein v-erbA on thyroid hormone-regulated genes in hepatocytes and their potential role in hepatocellular carcinoma. Molecular Biology Reports 38:2, pages 1137-1144.
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Arne Yndestad, John Willy Haukeland, Tuva B. Dahl, Bente Halvorsen & Pål Aukrust. 2011. Activins and Inhibins. Activins and Inhibins 323 342 .
Kai Yoshizawa, Hiroshi Abe, Yasuhito Kubo, Takuya Kitahara, Ryoichi Aizawa, Mika Matsuoka & Yoshio Aizawa. (2010) Expansion of CD4 + CD25 + FoxP3 + regulatory T cells in hepatitis C virus‐related chronic hepatitis, cirrhosis and hepatocellular carcinoma . Hepatology Research 40:2, pages 179-187.
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Arne Yndestad, John Willy Haukeland, Tuva Børresdatter Dahl, Kristian Bjøro, Ivar Prydz Gladhaug, Christ Berge, Jan Kristian Damås, Terese Haaland, Else Marit Løberg, Paul Linnestad, Kåre Birkeland, Zbigniew Konopski, Bente Halvorsen, Rolf Kristian Berge & Pål Aukrust. (2009) A Complex Role of Activin A in Non-Alcoholic Fatty Liver Disease. The American Journal of Gastroenterology 104:9, pages 2196-2205.
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Emanuel Kreidl. (2009) Activins and follistatins: Emerging roles in liver physiology and cancer. World Journal of Hepatology 1:1, pages 17.
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Alev Deli. (2008) Activins and activin antagonists in hepatocellular carcinoma. World Journal of Gastroenterology 14:11, pages 1699.
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Sonia B. JakowlewMichael Grusch, Chantal Rodgarkia-Dara, Wilfried Bursch & Rolf Schulte-Hermann. 2008. Transforming Growth Factor-β in Cancer Therapy, Volume I. Transforming Growth Factor-β in Cancer Therapy, Volume I 483 508 .
Chantal Rodgarkia-Dara, Susanne Vejda, Natascha Erlach, Annemarie Losert, Wilfried Bursch, Walter Berger, Rolf Schulte-Hermann & Michael Grusch. (2006) The activin axis in liver biology and disease. Mutation Research/Reviews in Mutation Research 613:2-3, pages 123-137.
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Anuradha Budhu & Xin Wei Wang. (2006) The role of cytokines in hepatocellular carcinoma. Journal of Leukocyte Biology 80:6, pages 1197-1213.
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K Breuhahn, T Longerich & P Schirmacher. (2006) Dysregulation of growth factor signaling in human hepatocellular carcinoma. Oncogene 25:27, pages 3787-3800.
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Willem Boers, Saida Aarrass, Chris Linthorst, Massimo Pinzani, Ronald Oude Elferink & Piter Bosma. (2006) Transcriptional Profiling Reveals Novel Markers of Liver Fibrogenesis. Journal of Biological Chemistry 281:24, pages 16289-16295.
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Mohamed Yousry Elsammak, Gamal M. Amin, Gehan M. Khalil, Wafaa S. Ragab & Mona M. Abaza. (2006) Possible contribution of serum activin A and IGF-1 in the development of hepatocellular carcinoma in Egyptian patients suffering from combined hepatitis C virus infection and hepatic schistosomiasis. Clinical Biochemistry 39:6, pages 623-629.
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Gaetano Leto, Lorena Incorvaia, Giuseppe Badalamenti, Francesca M. Tumminello, Nicola Gebbia, Carla Flandina, Marilena Crescimanno & Giovambattista Rini. (2006) Activin A circulating levels in patients with bone metastasis from breast or prostate cancer. Clinical & Experimental Metastasis 23:2, pages 117-122.
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Javier Oliver, Jose A. G. Agundez, Sonia Morales, Miguel Fernandez-Arquero, Benjamin Fernandez-Gutierrez, Emilio G. de la Concha, Manuel Diaz-Rubio, Javier Martin & Jose M. Ladero. (2005) Polymorphisms in the transforming growth factor-beta1 gene (TGF-beta1) and the risk of advanced alcoholic liver disease. Liver International 25:5, pages 935-939.
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C. Benckert, A. Thelen, A. Spinelli, G. Schumacher, P. Neuhaus & S. Jonas. 2005. Chirurgisches Forum 2005. Chirurgisches Forum 2005 3 5 .
Kristian L. Jones, David M. de Kretser, Shane. Patella & David J. Phillips. (2004) Activin A and follistatin in systemic inflammation. Molecular and Cellular Endocrinology 225:1-2, pages 119-125.
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Anja Germann, Susanne Dihlmann, Manfred Hergenhahn, Magnus von Knebel Doeberitz & Robert Koesters. (2003) Expression profiling of CC531 colon carcinoma cells reveals similar regulation of ?-catenin target genes by both butyrate and aspirin. International Journal of Cancer 106:2, pages 187-197.
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Robin D Hughes & Lee W Evans. (2003) Activin A and follistatin in acute liver failure. European Journal of Gastroenterology & Hepatology 15:2, pages 127-131.
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So Ya Paik, Young Nyun Park, Hoguen Kim & Chanil Park. (2003) Expression of Transforming Growth Factor-β1 and Transforming Growth Factor-β Receptors in Hepatocellular Carcinoma and Dysplastic Nodules. Modern Pathology 16:1, pages 86-96.
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R.E. Madrigal Domínguez, E. Saracíbar Serrador, M. Pérez-miranda castillo, R. Velicia Llames & A. Caro-Patón Gómez. (2002) Hepatocarcinoma de difícil diagnóstico. Gastroenterología y Hepatología 25:7, pages 481-482.
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