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Research Article

Faecal calprotectin and lactoferrin as markers of acute radiation proctitis: a pilot study of eight stool markers

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Pages 1113-1118 | Published online: 08 Jul 2009

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Mariana Nascimento, Cervantes Caporossi, José Eduardo Aguilar-Nascimento, Heloisa Michelon Castro-Barcellos, Rodrigo Teixeira Motta & Silvia Reis Lima. (2020) Efficacy of Synbiotics to Reduce Symptoms and Rectal Inflammatory Response in Acute Radiation Proctitis: A Randomized, Double-Blind, Placebo-Controlled Pilot Trial. Nutrition and Cancer 72:4, pages 602-609.
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Fei Sjöberg, Dilip Kumar Malipatlolla, Piyush Patel, Ulrica Wilderäng, Marie Kalm, Gunnar Steineck & Cecilia Bull. (2018) Elastase as a potential biomarker for radiation-induced gut wall injury of the distal bowel in an experimental mouse model. Acta Oncologica 57:8, pages 1025-1030.
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Andrea Hille, Margret Rave-Fränk, Hans Christiansen, Markus K. A. Herrmann, Tereza Kertesz, Robert M. Hermann, Hendrik A. Wolff, Markus Schirmer, Clemens F. Hess & Giuliano Ramadori. (2009) Faecal calprotectin and lactoferrin values during irradiation of prostate cancer correlate with chronic radiation proctitis: Results of a prospective study. Scandinavian Journal of Gastroenterology 44:8, pages 939-946.
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Andrea Hille, Emine Schmidt-Giese, Robert M. Hermann, Markus K. A. Herrmann, Margret Rave-Fränk, Markus Schirmer, Hans Christiansen, Clemens F. Hess & Giuliano Ramadori. (2008) A prospective study of faecal calprotectin and lactoferrin in the monitoring of acute radiation proctitis in prostate cancer treatment. Scandinavian Journal of Gastroenterology 43:1, pages 52-58.
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Annette Larsen, Benedikte Bjørge, Beate Klementsen, Lars Helgeland, Tore Wentzel-Larsen, Magne K. Fagerhol, Nils Hovdenak & Olav Dahl. (2007) Time patterns of changes in biomarkers, symptoms and histopathology during pelvic radiotherapy. Acta Oncologica 46:5, pages 639-650.
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Articles from other publishers (22)

Mitsuru Chiba, Haruka Uehara, Haruka Kuwata & Ikumi Niiyama. (2024) Extracellular miRNAs in the serum and feces of mice exposed to high‑dose radiation. Biomedical Reports 20:3.
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Roberta Vitali, Francesca Palone, Ilaria De Stefano, Chiara Fiorente, Flavia Novelli, Emanuela Pasquali, Emiliano Fratini, Mirella Tanori, Simona Leonardi, Barbara Tanno, Eleonora Colantoni, Sara Soldi, Serena Galletti, Maria Grimaldi, Alessio Giuseppe Morganti, Lorenzo Fuccio, Simonetta Pazzaglia, Claudio Pioli, Mariateresa Mancuso & Loredana Vesci. (2023) Characterization of Early and Late Damage in a Mouse Model of Pelvic Radiation Disease. International Journal of Molecular Sciences 24:10, pages 8800.
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Aditya ChilayDrDr, Neha MehraDrDr, Moumita MisraDrDr, Flavia Almeida, Kirti ChadhaDrDr, Raj Jatale & Shibani RamchandranDrDr. (2022) ROLE OF FECAL CALPROTECTIN FOR ASSESSMENT OF INFLAMMATORY BOWEL DISEASE ACTIVITY, 4-YEAR STUDY DONE IN INDIAN REFERENCE LABORATORY. INDIAN JOURNAL OF APPLIED RESEARCH, pages 33-35.
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Mutlu Keskin, Jenna Kompuinen, İlknur Harmankaya, Didem Karaçetin, Verneri Nissilä, Mervi Gürsoy, Timo Sorsa & Ulvi Kahraman Gürsoy. (2022) Oral Cavity Calprotectin and Lactoferrin Levels in Relation to Radiotherapy. Current Issues in Molecular Biology 44:10, pages 4439-4446.
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Sendhilnathan Ramalingam, Sharareh Siamakpour-Reihani, Lauren Bohannan, Yi Ren, Alexander Sibley, Jeff Sheng, Li Ma, Andrew B. Nixon, Jing Lyu, Daniel C. Parker, James Bain, Michael Muehlbauer, Olga Ilkayeva, Virginia Byers Kraus, Janet L. Huebner, Thomas Spitzer, Jami Brown, Jonathan U. Peled, Marcel van den Brink, Antonio Gomes, Taewoong Choi, Cristina Gasparetto, Mitchell Horwitz, Gwynn Long, Richard Lopez, David Rizzieri, Stefanie Sarantopoulos, Nelson Chao & Anthony D. Sung. (2021) A phase 2 trial of the somatostatin analog pasireotide to prevent GI toxicity and acute GVHD in allogeneic hematopoietic stem cell transplant. PLOS ONE 16:6, pages e0252995.
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Ben G.L. Vanneste, Evert J. Van Limbergen, Tom Marcelissen, Kobe Reynders, Jarno Melenhorst, Joep G.H. van Roermund & Ludy Lutgens. (2021) Is prostate cancer radiotherapy using implantable rectum spacers safe and effective in inflammatory bowel disease patients?. Clinical and Translational Radiation Oncology 27, pages 121-125.
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Ainaz Sourati, Ahmad Ameri & Mona MalekzadehAinaz Sourati, Ahmad Ameri & Mona Malekzadeh. 2017. Acute Side Effects of Radiation Therapy. Acute Side Effects of Radiation Therapy 165 172 .
Özgür Dandin, Mehmet Levhi Akin, Ahmet Ziya Balta, Ergün Yücel, Dursun Özgür Karakaş, Sezai Demirbaş, Sevim Özdemir & Apdullah Haholu. (2013) The Efficacy of Probiotic (Lactobacillus rhamnosus GG) and 5-ASA (Aminosalicylic Acid) in the Treatment of Experimental Radiation Proctitis in Rats. Indian Journal of Surgery 77:S2, pages 563-569.
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Ahmad Al-Saffar, André Nogueira da Costa, Annie Delaunois, Derek J. Leishman, Louise Marks, Marie-Luce Rosseels & J.-P. Valentin. 2015. Principles of Safety Pharmacology. Principles of Safety Pharmacology 291 321 .
Dominique Legrand. (2012) Lactoferrin, a key molecule in immune and inflammatory processes 1 This article is part of Special Issue entitled Lactoferrin and has undergone the Journal’s usual peer review process. . Biochemistry and Cell Biology 90:3, pages 252-268.
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Caroline C. Henson & Yeng S. Ang. (2012) Biomarkers of normal tissue toxicity after pelvic radiotherapy. Current Opinion in Supportive & Palliative Care 6:1, pages 33-40.
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Linda J Wedlake & H Jervoise N Andreyev. (2011) Manipulating the consequential effect: an alternative approach to reducing pelvic radiation disease other than dose reduction. Current Opinion in Supportive & Palliative Care 5:1, pages 25-28.
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Gianmichele Meucci, Renata D’Incà, Roberto Maieron, Nicoletta Orzes, Maurizio Vecchi, Daniela Visentini, Giorgio Minoli, Elisabetta Dal Pont, Maurizio Zilli, Elvio Benedetti, Tiziana Virgilio & Elio Tonutti. (2010) Diagnostic value of faecal calprotectin in unselected outpatients referred for colonoscopy: A multicenter prospective study. Digestive and Liver Disease 42:3, pages 191-195.
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V.S. Theis, R. Sripadam, V. Ramani & S. Lal. (2010) Chronic Radiation Enteritis. Clinical Oncology 22:1, pages 70-83.
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E. VARELA, M. ANTOLÍN, F. GUARNER, R. VERGES, J. GIRALT & J.‐R. MALAGELADA. (2013) Faecal DNA and calprotectin as biomarkers of acute intestinal toxicity in patients undergoing pelvic radiotherapy. Alimentary Pharmacology & Therapeutics 30:2, pages 175-185.
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H Huang. (2008) Advances in treatment of radiation proctitis. Journal of Chinese Integrative Medicine 6:9, pages 975-978.
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C. MCGOUGH, L. WEDLAKE, C. BALDWIN, C. HACKETT, A. R. NORMAN, P. BLAKE, K. HARRINGTON, D. TAIT, V. KHOO, G. FROST & H. J. N. ANDREYEV. (2008) Clinical trial: normal diet vs. partial replacement with oral E028 formula for the prevention of gastrointestinal toxicity in cancer patients undergoing pelvic radiotherapy. Alimentary Pharmacology & Therapeutics 27:11, pages 1132-1139.
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L. WEDLAKE, C. McGOUGH, C. HACKETT, K. THOMAS, P. BLAKE, K. HARRINGTON, D. TAIT, V. KHOO, D. DEARNALEY & H. J. N. ANDREYEV. (2008) Can biological markers act as non‐invasive, sensitive indicators of radiation‐induced effects in the gastrointestinal mucosa?. Alimentary Pharmacology & Therapeutics 27:10, pages 980-987.
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Jun-Ying Xiang, Qin Ouyang, Guo-Dong Li & Nan-Ping Xiao. (2008) Clinical value of fecal calprotectin in determining disease activity of ulcerative colitis. World Journal of Gastroenterology 14:1, pages 53.
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A. Loganayagam & I. Bjarnason. 2008. IBD 2007 — Achievements in Research and Clinical Practice. IBD 2007 — Achievements in Research and Clinical Practice 129 142 .
Renata D’Incà, Elisabetta Dal Pont, Vincenza Di Leo, Antonio Ferronato, Walter Fries, Maria Grazia Vettorato, Diego Martines & Giacomo Carlo Sturniolo. (2006) Calprotectin and lactoferrin in the assessment of intestinal inflammation and organic disease. International Journal of Colorectal Disease 22:4, pages 429-437.
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I. Bjarnason, L. Maiden & K. Takeuchi. 2005. Gastroenterology Yesterday — Today — Tomorrow: A Review and Preview. Gastroenterology Yesterday — Today — Tomorrow: A Review and Preview 253 266 .

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