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Scandinavian Journal of Gastroenterology Volume 42, 2007 - Issue 5
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ORIGINAL ARTICLE

Deficient activity of mammalian prolyl oligopeptidase on the immunoactive peptide digestion in coeliac disease

J. Arturo Garcia-Horsman Centro de Investigación Príncipe Felipe, Valencia, Spain; Department of Pharmacology and Toxicology, Kuopio University, Kuopio, FinlandCorrespondence[email protected]
, PhD,
Jarkko I. Venäläinen Department of Pharmacology and Toxicology, Kuopio University, Kuopio, Finland
,
Olli Lohi Paediatric Research Centre, Tampere University Medical School and Tampere University Hospital, Tampere, Finland
,
I. Seppo Auriola Department of Pharmaceutical Chemistry, Kuopio University, Kuopio, Finland
,
Ilma R. Korponay-Szabo Paediatric Research Centre, Tampere University Medical School and Tampere University Hospital, Tampere, Finland
,
Katri Kaukinen Paediatric Research Centre, Tampere University Medical School and Tampere University Hospital, Tampere, Finland; Gastroenterology and Alimentary Tract Surgery, Tampere University Hospital, Tampere, Finland
,
Markku Mäki Paediatric Research Centre, Tampere University Medical School and Tampere University Hospital, Tampere, Finland
&
Pekka T. Männistö Department of Pharmacology and Toxicology, Kuopio University, Kuopio, Finland; Division of Pharmacology and Toxicology, Pharmacy Faculty, University of Helsinki, Finland
 show all
Pages 562-571 | Received 22 Mar 2006, Published online: 08 Jul 2009

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Hugh James Freeman. (2015) Emerging drugs for celiac disease. Expert Opinion on Emerging Drugs 20:1, pages 129-135.
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Kalle Kurppa, Minna Hietikko, Ana-Marija Sulic, Katri Kaukinen & Katri Lindfors. (2014) Current status of drugs in development for celiac disease. Expert Opinion on Investigational Drugs 23:8, pages 1079-1091.
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Katri Lindfors, Marja-Leena Lähdeaho, Suvi Kalliokoski, Kalle Kurppa, Pekka Collin, Markku Mäki & Katri Kaukinen. (2012) Future treatment strategies for celiac disease. Expert Opinion on Therapeutic Targets 16:7, pages 665-675.
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Satumarja M. Stenman, Jarkko I. Venäläinen, Katri Lindfors, Seppo Auriola, Timo Mauriala, Anu Kaukovirta-Norja, Anna Jantunen, Kaija Laurila, Shuo-Wang Qiao, Ludvig M. Sollid, Pekka T. Männistö, Katri Kaukinen & Markku Mäki. (2009) Enzymatic detoxification of gluten by germinating wheat proteases: Implications for new treatment of celiac disease. Annals of Medicine 41:5, pages 390-400.
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Articles from other publishers (13)

Andrea Polo, Kashika Arora, Hana Ameur, Raffaella Di Cagno, Maria De Angelis & Marco Gobbetti. (2020) Gluten-free diet and gut microbiome. Journal of Cereal Science 95, pages 103058.
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Shakira Yoosuf & Govind K. Makharia. (2019) Evolving Therapy for Celiac Disease. Frontiers in Pediatrics 7.
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Massimo Venditti & Sergio Minucci. (2018) Subcellular Localization of Prolyl Endopeptidase During the First Wave of Rat Spermatogenesis and in Rat and Human Sperm. Journal of Histochemistry & Cytochemistry 67:4, pages 229-243.
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Marco Gobbetti, Erica Pontonio, Pasquale Filannino, Carlo Giuseppe Rizzello, Maria De Angelis & Raffaella Di Cagno. (2018) How to improve the gluten-free diet: The state of the art from a food science perspective. Food Research International 110, pages 22-32.
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Zsuzsa Szondy, Ilma Korponay-Szabó, Robert Király, Zsolt Sarang & Gregory J. Tsay. (2017) Transglutaminase 2 in human diseases. BioMedicine 7:3, pages 15.
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Hugh J. Freeman. (2015) Celiac Disease: A Disorder Emerging from Antiquity, Its Evolving Classification and Risk, and Potential New Treatment Paradigms. Gut and Liver 9:1, pages 28-37.
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Katri Kaukinen, Katri Lindfors & Markku Mäki. (2013) Advances in the treatment of coeliac disease: an immunopathogenic perspective. Nature Reviews Gastroenterology & Hepatology 11:1, pages 36-44.
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Zsuzsa Szondy, Ilma Korponay‐Szabó, Róbert Király & László Fésüs. 2011. Advances in Enzymology. Advances in Enzymology 295 345 .
M.J. Moreno-Baylach, V. Felipo, P.T. Männistö & J.A. García-Horsman. (2008) Expression and traffic of cellular prolyl oligopeptidase are regulated during cerebellar granule cell differentiation, maturation, and aging. Neuroscience 156:3, pages 580-585.
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Jofre Tenorio‐Laranga, Jarkko I. Venäläinen, Pekka T. Männistö & J. A. García‐Horsman. (2008) Characterization of membrane‐bound prolyl endopeptidase from brain. The FEBS Journal 275:17, pages 4415-4427.
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John M Hutchinson, Gerry Robins & Peter D Howdle. (2008) Advances in coeliac disease. Current Opinion in Gastroenterology 24:2, pages 129-134.
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K Juuti-Uusitalo, M Mäki, H Kainulainen, J Isola & K Kaukinen. (2007) Gluten affects epithelial differentiation-associated genes in small intestinal mucosa of coeliac patients. Clinical and Experimental Immunology 150:2, pages 294-305.
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J.A. García-Horsman, P.T. Männistö & J.I. Venäläinen. (2007) On the role of prolyl oligopeptidase in health and disease. Neuropeptides 41:1, pages 1-24.
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