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Scandinavian Journal of Gastroenterology Volume 42, 2007 - Issue 10
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ORIGINAL ARTICLE

Fecal pyruvate kinase: A potential new marker for intestinal inflammation in children with inflammatory bowel disease

Elżbieta Czub Department of Infectious Diseases, Child & Mother Specialist Hospital in Poznan, Poznan, Poland
,
Karl-Heinz Herzig A.I. Virtanen Institute for Molecular Sciences, and Department of Internal Medicine, KYS, University of Kuopio,
,
Anna Szaflarska-Popławska Chair of Pediatrics, Gastroenterology and Alergology, Collegium Medicum, Mikolaj Kopernik University, Torun, Poland
,
Karlheinz Kiehne I. Department of Medicine, UKSH, Christian-Albrechts-University, Kiel, Germany
,
Piotr Socha Child Health Memorial Institute, Department of Gastroenterology, Hepatology and Immunology, Warsaw, Poland
,
Halina Woś Department of Pediatrics, Silesian Medical University, Katowice, Poland
,
Barbara Kamińska Clinic of Pediatrics, Pediatric Gastroenterology and Oncology, Medical University of Gdansk, Poland
,
Michal Błaszczyński Chair of Pediatric Surgery, Traumatology and Urology, Poznan University of Medical Sciences, Poland
,
Wojciech Cichy I. Chair of Pediatrics, Department of Gastroenterology & Metabolism, Poznan University of Medical Sciences, Poznan, Poland; Departmnt of Physiology, Oulu University, Finland
,
Grażyna Bała I. Department of Medicine, UKSH, Christian-Albrechts-University, Kiel, Germany
,
Jacek Brodzicki Clinic of Pediatrics, Pediatric Gastroenterology and Oncology, Medical University of Gdansk, Poland
,
Urszula Grzybowska-Chlebowczyk Department of Pediatrics, Silesian Medical University, Katowice, Poland
&
Jarosław Walkowiak I. Chair of Pediatrics, Department of Gastroenterology & Metabolism, Poznan University of Medical Sciences, Poznan, Poland; Departmnt of Physiology, Oulu University, FinlandCorrespondence[email protected]
, MD show all
Pages 1147-1150 | Received 10 Jan 2007, Published online: 08 Jul 2009

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Cong Dai, Min Jiang & Ming-Jun Sun. (2018) Fecal markers in the management of inflammatory bowel disease. Postgraduate Medicine 130:7, pages 597-606.
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A El-Ansary, S Al-Daihan, A Al-Dabas & L Al-Ayadhi. (2010) Activities of key glycolytic enzymes in the plasma of Saudi autistic patients. Open Access Journal of Clinical Trials 2, pages 49-57.
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Articles from other publishers (26)

Gabriele Dragoni, Tommaso Innocenti & Andrea Galli. (2021) Biomarkers of Inflammation in Inflammatory Bowel Disease: How Long before Abandoning Single-Marker Approaches?. Digestive Diseases 39:3, pages 190-203.
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Rayna Shentova-Eneva & Tsvetelina Velikova. (2020) Laboratory Assessment of Disease Activity in Pediatric Patients with Inflammatory Bowel Disease: What’s New?. Gastroenterology Insights 11:2, pages 58-71.
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Steven T. Leach, Andrew S. Day, Rachel Messenger, Thomas D. Walters, Victor M. Navas-López, Malgorzata Sladek, Annecarin Brückner, Baruch Yerushalmi, Shehzad Saeed, Anthony Otley, David Mack, Matan Gavish, Dan Turner, Anne M. Griffiths & Daniel A. Lemberg. (2020) Fecal Markers of Inflammation and Disease Activity in Pediatric Crohn Disease: Results from the ImageKids Study. Journal of Pediatric Gastroenterology & Nutrition 70:5, pages 580-585.
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Mirko Di Ruscio, Filippo Vernia, Antonio Ciccone, Giuseppe Frieri & Giovanni Latella. (2018) Surrogate Fecal Biomarkers in Inflammatory Bowel Disease: Rivals or Complementary Tools of Fecal Calprotectin?. Inflammatory Bowel Diseases 24:1, pages 78-92.
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Gilles Duvoisin, Robert N. Lopez, Andrew S. Day, Daniel A. Lemberg, Richard B. Gearry & Steven T. Leach. (2017) Novel Biomarkers and the Future Potential of Biomarkers in Inflammatory Bowel Disease. Mediators of Inflammation 2017, pages 1-9.
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Floris AE De Voogd, Richard B Gearry, Christopher J Mulder & Andrew S Day. (2016) Osteoprotegerin: A novel biomarker for inflammatory bowel disease and gastrointestinal carcinoma. Journal of Gastroenterology and Hepatology 31:8, pages 1386-1392.
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Oscar R. Herrera, Michael L. Christensen & Richard A. Helms. (2016) Calprotectin: Clinical Applications in Pediatrics. The Journal of Pediatric Pharmacology and Therapeutics 21:4, pages 308-321.
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. 2016. Molecular Microbiology. Molecular Microbiology 663 682 .
Dorota Roszak, Mirosława Gałęcka, Wojciech Cichy & Patrycja Szachta. (2015) Determination of faecal inflammatory marker concentration as a noninvasive method of evaluation of pathological activity in children with inflammatory bowel diseases. Advances in Medical Sciences 60:2, pages 246-252.
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Tamara Pang, Steven T Leach, Tamarah Katz, Adam Jaffe, Andrew S Day & Chee Y Ooi. (2015) Elevated fecal M2-pyruvate kinase in children with cystic fibrosis: A clue to the increased risk of intestinal malignancy in adulthood?. Journal of Gastroenterology and Hepatology 30:5, pages 866-871.
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Qiyun Tang, Qianqian Ji, Weiwei Xia, Liren Li, Jian’an Bai, Runzhou Ni & Yongwei Qin. (2014) Pyruvate Kinase M2 Regulates Apoptosis of Intestinal Epithelial Cells in Crohn’s Disease. Digestive Diseases and Sciences 60:2, pages 393-404.
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Frank S. Lehmann, Emanuel Burri & Christoph Beglinger. (2014) The role and utility of faecal markers in inflammatory bowel disease. Therapeutic Advances in Gastroenterology 8:1, pages 23-36.
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Elzbieta Czub, Jan K. Nowak, Jerzy Moczko, Aleksandra Lisowska, Aleksandra Banaszkiewicz, Tomasz Banasiewicz & Jaroslaw Walkowiak. (2014) Comparison of fecal pyruvate kinase isoform M2 and calprotectin in acute diarrhea in hospitalized children. Scientific Reports 4:1.
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Uri Kopylov, Greg Rosenfeld, Brian Bressler & Ernest Seidman. (2014) Clinical Utility of Fecal Biomarkers for the Diagnosis and Management of Inflammatory Bowel Disease. Inflammatory Bowel Diseases 20:4, pages 742-756.
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Yi Fengming & Wu Jianbing. (2014) Biomarkers of Inflammatory Bowel Disease. Disease Markers 2014, pages 1-11.
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Kang-Moon Lee. (2013) Fecal Biomarkers in Inflammatory Bowel Disease. Intestinal Research 11:2, pages 73.
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Roy A Sherwood. (2012) Faecal markers of gastrointestinal inflammation. Journal of Clinical Pathology 65:11, pages 981-985.
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A. S. Day, T. Judd, D. A. Lemberg & S. T. Leach. (2012) Fecal M2-PK in Children with Crohn’s Disease: A Preliminary Report. Digestive Diseases and Sciences 57:8, pages 2166-2170.
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Thomas A Judd, Andrew S Day, Daniel A Lemberg, Dan Turner & Steven T Leach. (2011) Update of fecal markers of inflammation in inflammatory bowel disease. Journal of Gastroenterology and Hepatology 26:10, pages 1493-1499.
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Francisco A. Sylvester, Dan Turner, Andrew Draghi, Krista Uuosoe, Robin McLernon, Kristen Koproske, David R. Mack, Wallace V. Crandall, Jeffrey S. Hyams, Neal S. LeLeiko & Anne M. Griffiths. (2011) Fecal osteoprotegerin may guide the introduction of second-line therapy in hospitalized children with ulcerative colitis. Inflammatory Bowel Diseases 17:8, pages 1726-1730.
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James D. Lewis. (2011) The Utility of Biomarkers in the Diagnosis and Therapy of Inflammatory Bowel Disease. Gastroenterology 140:6, pages 1817-1826.e2.
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Carol B. Lindsley & Ronald M. Laxer. 2011. Textbook of Pediatric Rheumatology. Textbook of Pediatric Rheumatology 298 304 .
Shilpa Joshi, Stephen J Lewis, Siobhan Creanor & Ruth M Ayling. (2009) Age-related faecal calprotectin, lactoferrin and tumour M2-PK concentrations in healthy volunteers. Annals of Clinical Biochemistry: International Journal of Laboratory Medicine 47:3, pages 259-263.
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Cansel Turkay & Benan Kasapoglu. (2010) Noninvasive methods in evaluation of inflammatory bowel disease: where do we stand now? An update. Clinics 65:2, pages 221-231.
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Jinny Jeffery, Stephen J. Lewis & Ruth M. Ayling. (2009) Fecal dimeric M2-pyruvate kinase (tumor M2-PK) in the differential diagnosis of functional and organic bowel disorders. Inflammatory Bowel Diseases 15:11, pages 1630-1634.
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Shailendra Kapoor. (2008) Novel new noninvasive biomarkers of inflammatory bowel disease. Inflammatory Bowel Diseases 14:9, pages 1317.
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