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Research Article

High Prevalence of Antibodies to Calreticulin of the IgA Class in Primary Biliary Cirrhosis: a Possible Role of Gut-Derived Bacterial Antigens in Its Aetiology?

Pages 623-628 | Published online: 08 Jul 2009

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C. S. Jørgensen, K. B. Hansen, S. Jacobsen, P. Halberg, S. Ullman, D. Hansen, T. L. Mikkelsen, B. Weile, M. H. Madsen, A. Wiik & G. Houen. (2005) Absence of high‐affinity calreticulin autoantibodies in patients with systemic rheumatic diseases and coeliac disease. Scandinavian Journal of Clinical and Laboratory Investigation 65:5, pages 403-412.
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Pu Song, Weigang Zhang, Sen Guo, Gang Wang, Tianwen Gao, Chunying Li & Ling Liu. (2024) Membranal Expression of Calreticulin Induced by Unfolded Protein Response in Melanocytes: A Mechanism Underlying Oxidative Stress–Induced Autoimmunity in Vitiligo. Journal of Investigative Dermatology.
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Paul Eggleton, Jorge De Alba, Michael Weinreich, Perry Calias, Roly Foulkes & Valerie M. Corrigall. (2023) The therapeutic mavericks: Potent immunomodulating chaperones capable of treating human diseases. Journal of Cellular and Molecular Medicine 27:3, pages 322-339.
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Endrit Shahini, Giuseppe Pasculli, Andrea Mastropietro, Paola Stolfi, Paolo Tieri, Davide Vergni, Raffaele Cozzolongo, Francesco Pesce & Gianluigi Giannelli. (2022) Network Proximity-Based Drug Repurposing Strategy for Early and Late Stages of Primary Biliary Cholangitis. Biomedicines 10:7, pages 1694.
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María-José Barrera, Sergio Aguilera, Isabel Castro, Sergio González, Patricia Carvajal, Claudio Molina, Marcela A. Hermoso & María-Julieta González. (2018) Endoplasmic reticulum stress in autoimmune diseases: Can altered protein quality control and/or unfolded protein response contribute to autoimmunity? A critical review on Sjögren's syndrome. Autoimmunity Reviews 17:8, pages 796-808.
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Stewart Siyan Cao, Katherine L. Luo & Lynn Shi. (2015) Endoplasmic Reticulum Stress Interacts With Inflammation in Human Diseases. Journal of Cellular Physiology 231:2, pages 288-294.
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Valerie R. Wiersma, Marek Michalak, Trefa M. Abdullah, Edwin Bremer & Paul Eggleton. (2015) Mechanisms of Translocation of ER Chaperones to the Cell Surface and Immunomodulatory Roles in Cancer and Autoimmunity. Frontiers in Oncology 5.
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D Hannani, C Locher, T Yamazaki, V Colin-Minard, M Vetizou, L Aymeric, S Viaud, D Sanchez, M J Smyth, P Bruhns, G Kroemer & L Zitvogel. (2013) Contribution of humoral immune responses to the antitumor effects mediated by anthracyclines. Cell Death & Differentiation 21:1, pages 50-58.
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Maria Papp, Nora Sipeki, Zsuzsanna Vitalis, Tamas Tornai, Istvan Altorjay, Istvan Tornai, Miklos Udvardy, Kai Fechner, Silvia Jacobsen, Bianca Teegen, Andrea Sumegi, Gabor Veres, Peter Laszlo Lakatos, Janos Kappelmayer & Peter Antal-Szalmas. (2013) High prevalence of IgA class anti-neutrophil cytoplasmic antibodies (ANCA) is associated with increased risk of bacterial infection in patients with cirrhosis. Journal of Hepatology 59:3, pages 457-466.
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Leslie I. Gold, Paul Eggleton, Mariya T. Sweetwyne, Lauren B. Van Duyn, Matthew R. Greives, Sara‐Megumi Naylor, Marek Michalak & Joanne E. Murphy‐Ullrich. (2009) Calreticulin: non‐endoplasmic reticulum functions in physiology and disease. The FASEB Journal 24:3, pages 665-683.
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KAZUMICHI ABE, HIROMASA OHIRA, HIROKO KOBAYASHI, HIRONOBU SAITO, ATSUSHI TAKAHASHI, TSUYOSHI RAI, YUKIKO KANNO, KYOKO MONOE, HIROSHI WATANABE, ATSUSHI IRISAWA & YUKIO SATO. (2007) BREAKTHROUGH OF IMMUNE SELF-TOLERANCE TO CALRETICULIN INDUCED BY CpG-OLIGODEOXYNUCLEOTIDES AS ADJUVANT. FUKUSHIMA JOURNAL OF MEDICAL SCIENCE 53:2, pages 95-108.
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KENYA WATANABE, HIROMASA OHIRA, HIROSHI ORIKASA, KEIETSU SAITO, KAORI KANNO, YASUO SHIOYA, KATSUTOSHI OBARA & YUKIO SATO. (2006) ANTI-CALRETICULIN ANTIBODIES IN PATIENTS WITH INFLAMMATORY BOWEL DISEASE. FUKUSHIMA JOURNAL OF MEDICAL SCIENCE 52:1, pages 1-11.
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M. F. Bassendine. 2005. Autoimmune Liver Disease. Autoimmune Liver Disease 117 126 .
ChulHee Kang. 2012. Encyclopedia of Inorganic and Bioinorganic Chemistry. Encyclopedia of Inorganic and Bioinorganic Chemistry.
ChulHee Kang. 2004. Handbook of Metalloproteins. Handbook of Metalloproteins.
Eric Ballot, Olivia Bandin, Olivier Chazouilleres, Catherine Johanet & Raoul Poupon. (2004) Immune response to lipopolysaccharide in primary biliary cirrhosis and autoimmune diseases. Journal of Autoimmunity 22:2, pages 153-158.
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Sylvaine F.A Bruggraber, Patrick S.C Leung, Katsushi Amano, Chao Quan, Mark J Kurth, Michael H Nantz, Gordon D Benson, Judy Van de Water, Velimer Luketic, Thomas E Roche, Aftab A Ansari, Ross L Coppel & M.Eric Gershwin. (2003) Autoreactivity to lipoate and a conjugated form of lipoate in primary biliary cirrhosis. Gastroenterology 125:6, pages 1705-1713.
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Daniel Sánchez, Ludmila Tučková, Thomas Mothes, Wolfgang Kreisel, Zdeněk Beneš & Helena Tlaskalová-Hogenová. (2003) Epitopes of calreticulin recognised by IgA autoantibodies from patients with hepatic and coeliac disease. Journal of Autoimmunity 21:4, pages 383-392.
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Marc A Seelen, L A Trouw & M R Daha. (2003) Diagnostic and prognostic significance of anti-C1q antibodies in systemic lupus erythematosus. Current Opinion in Nephrology and Hypertension 12:6, pages 619-624.
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E V STAIKOU, J G ROUTSIAS, A A MAKRI, A TERZOGLOU, M SAKARELLOS-DAITSIOTIS, C SAKARELLOS, G PANAYOTOU, H M MOUTSOPOULOS & A G TZIOUFAS. (2003) Calreticulin binds preferentially with B cell linear epitopes of Ro60 kD autoantigen, enhancing recognition by anti-Ro60 kD autoantibodies. Clinical and Experimental Immunology 134:1, pages 143-150.
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Kenichi Harada, Satoru Ozaki, Yoshiko Sudo, Koichi Tsuneyama, Hajime Ohta & Yasuni Nakanuma. (2003) Osteopontin is involved in the formation of epithelioid granuloma and bile duct injury in primary biliary cirrhosis. Pathology International 53:1, pages 8-17.
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James Neuberger. (2002) Antibodies and primary biliary cirrhosis – piecing together the jigsaw. Journal of Hepatology 36:1, pages 126-129.
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Dimitrios-Petrou Bogdanos, Harold Baum, Umesh C Sharma, Alessandro Grasso, Yun Ma, Andrew K Burroughs & Diego Vergani. (2002) Antibodies against homologous microbial caseinolytic proteases P characterise primary biliary cirrhosis. Journal of Hepatology 36:1, pages 14-21.
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Anup Ramachandran & Kunnissery A Balasubramanian. (2001) Intestinal dysfunction in liver cirrhosis: Its role in spontaneous bacterial peritonitis. Journal of Gastroenterology and Hepatology 16:6, pages 607-612.
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D Sánchez, L Tučková, P Šebo, M Michalak, A Whelan, I Šterzl, L Jelı́nková, E Havrdová, M Imramovská, Z Beneš, S Krupičková & H Tlaskalová-Hogenová. (2000) Occurrence of IgA and IgG Autoantibodies to Calreticulin in Coeliac Disease and Various Autoimmune Diseases. Journal of Autoimmunity 15:4, pages 441-449.
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