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Original Article

Evaluation of the immunogenicity and reactogenicity of a DTPa-HBV-IPV combination vaccine Co-administered with a hib conjugate vaccine either as a single injection of a hexavalent combination or as two separate injections at 3, 5 and 11 months of age

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Pages 585-592 | Received 22 Dec 2003, Accepted 26 May 2004, Published online: 08 Jul 2009

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Read on this site (7)

Vincenzo Baldo, Paolo Bonanni, Marcela Castro, Giovanni Gabutti, Elisabetta Franco, Federico Marchetti, Rosa Prato & Francesco Vitale. (2014) Combined hexavalent diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliovirus-Haemophilus influenzae type b vaccine; Infanrix™ hexa. Human Vaccines & Immunotherapeutics 10:1, pages 129-137.
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Fred Zepp, Heinz-Josef Schmitt, Jan Cleerbout, Thomas Verstraeten, Lode Schuerman & Jeanne-Marie Jacquet. (2009) Review of 8 years of experience with Infanrix hexa™ (DTPa–HBV–IPV/Hib hexavalent vaccine). Expert Review of Vaccines 8:6, pages 663-678.
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Naor Bar-Zeev & Jim P Buttery. (2006) Combination conjugate vaccines. Expert Opinion on Drug Safety 5:3, pages 351-360.
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Bei Liu, Bing Cao, Chao Wang, Bingfeng Han, Tao Sun, Yudong Miao, Qingbin Lu & Fuqiang Cui. (2022) Immunogenicity and Safety of Childhood Combination Vaccines: A Systematic Review and Meta-Analysis. Vaccines 10:3, pages 472.
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Marilou Kiely, Marie-Noëlle Billard, Eveline Toth, Joseline G. Zafack, Monique Landry, Danuta M. Skowronski & Gaston De Serres. (2018) Investigation of an increase in large local reactions following vaccine schedule change to include DTaP-HB-IPV-Hib (Infanrix-hexa®) and MMRV (ProQuad®) at 18 months of age. Vaccine 36:45, pages 6688-6694.
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Pablo Obando-Pacheco, Irene Rivero-Calle, José Gómez-Rial, Carmen Rodríguez-Tenreiro Sánchez & Federico Martinón-Torres. (2018) New perspectives for hexavalent vaccines. Vaccine 36:36, pages 5485-5494.
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Susana Monge, Susan JM Hahné, Hester E de Melker, Elisabeth AM Sanders, Arie van der Ende & Mirjam J Knol. (2018) Effectiveness of the DTPa-HBV-IPV/Hib vaccine against invasive Haemophilus influenzae type b disease in the Netherlands (2003–16): a case-control study. The Lancet Infectious Diseases 18:7, pages 749-757.
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Michael D. Decker, Kathryn M. Edwards & Barbara J. Howe. 2018. Plotkin's Vaccines. Plotkin's Vaccines 198 227.e13 .
Timo Vesikari, Sven-Arne Silfverdal, Emilia Jordanov & Emmanuel Feroldi. (2017) A Randomized, Controlled Study of DTaP-IPV-HB-PRP-T, a Fully Liquid Hexavalent Vaccine, Administered in a 3-, 5- and 11- to 12-month Schedule. Pediatric Infectious Disease Journal 36:1, pages 87-93.
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David W. Scheifele, Murdo Ferguson, Gerald Predy, Meena Dawar, Deepak Assudani, Sherine Kuriyakose, Olivier Van Der Meeren & Htay-Htay Han. (2015) Immunogenicity and safety of 3-dose primary vaccination with combined DTPa-HBV-IPV/Hib vaccine in Canadian Aboriginal and non-Aboriginal infants. Vaccine 33:16, pages 1897-1900.
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S. Esposito, C. Tagliabue, S. Bosis, V. Ierardi, M. Gambino & N. Principi. (2014) Hexavalent vaccines for immunization in paediatric age. Clinical Microbiology and Infection 20, pages 76-85.
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Timo Vesikari, Aino Forstén, Maria Guiseppina Desole, Giuseppe Ferrera, Magalie Caubet, Narcisa Mesaros & Dominique Boutriau. (2013) A Combined Haemophilus influenzae Type B Neisseria meningitidis Serogroup C Tetanus Toxoid Conjugate Vaccine Is Immunogenic and Well-tolerated When Coadministered With Diphtheria, Tetanus, Acellular Pertussis Hepatitis B–inactivated Poliovirus at 3, 5 and 11 Months of Age. Pediatric Infectious Disease Journal 32:5, pages 521-529.
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Michael D. Decker, Kathryn M. Edwards & Hugues H. Bogaerts. 2013. Vaccines. Vaccines 981 1007 .
Katherine A. Lyseng-Williamson & Sohita Dhillon. (2012) DTPa-HBV-IPV/Hib Vaccine (Infanrix hexa™): A Guide to Its Use in Infants. Pediatric Drugs 14:5, pages 337-343.
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Katherine A. Lyseng-Williamson & Sohita Dhillon. (2012) DTPa-HBV-IPV/Hib Vaccine (Infanrix hexa™): A Guide to Its Use in Infants. Pediatric Drugs 14:5, pages 337-343.
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Edna S Bar-On, Elad Goldberg, Sarah Hellmann & Leonard Leibovici. (2012) Combined DTP-HBV-HIB vaccine versus separately administered DTP-HBV and HIB vaccines for primary prevention of diphtheria, tetanus, pertussis, hepatitis B and Haemophilus influenzae B (HIB) . Cochrane Database of Systematic Reviews.
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Olivier Van Der Meeren, Sherine Kuriyakose, Devayani Kolhe & Karin Hardt. (2012) Immunogenicity of Infanrix™ hexa administered at 3, 5 and 11 months of age. Vaccine 30:17, pages 2710-2714.
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Pei-Lan Shao, Chun-Yi Lu, Yu-Chia Hsieh, Hans L Bock & Li-Min Huang. (2011) Immunogenicity and Reactogenicity of Diphtheria—Tetanus—Acellular Pertussis—Hepatitis B—Inactivated Poliovirus and Haemophilus influenzae Type B Vaccines Administered Concomitantly to Infants as a Three-dose Primary Course. Journal of the Formosan Medical Association 110:5, pages 336-341.
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Edna S Bar‐On, Elad Goldberg, Abigail Fraser, Liat Vidal, Sarah Hellmann & Leonard Leibovici. (2011) Cochrane Review: Combined DTP‐HBV‐HIB vaccine versus separately administered DTP‐HBV and HIB vaccines for primary prevention of diphtheria, tetanus, pertussis, hepatitis B and Haemophilus influenzae B (HIB). Evidence-Based Child Health: A Cochrane Review Journal 6:1, pages 7-65.
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Sohita Dhillon. (2010) Spotlight on DTPa-HBV-IPV/Hib Vaccine (Infanrix hexa™)†. BioDrugs 24:5, pages 299-302.
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Sohita Dhillon. (2010) DTPa-HBV-IPV/Hib Vaccine (Infanrix hexa™). Drugs 70:8, pages 1021-1058.
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Edna S Bar-On, Elad Goldberg, Abigail Fraser, Liat Vidal, Sarah Hellmann & Leonard Leibovici. 1996. Cochrane Database of Systematic Reviews. Cochrane Database of Systematic Reviews.
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Liliana Vázquez, Fabiana Garcia, Ricardo Rüttimann, Gustavo Coconier, Jeanne-Marie Jacquet & Lode Schuerman. (2008) Immunogenicity and reactogenicity of DTPa-HBV-IPV/Hib vaccine as primary and booster vaccination in low-birth-weight premature infants. Acta Paediatrica 97:9, pages 1243-1249.
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Fong-Seng Lim, Htay-Htay Han, Jeanne-Marie Jacquet & Hans L Bock. (2007) Primary Vaccination of Infants Against Hepatitis B can be Completed Using a Combined Hexavalent Diphtheria-tetanus-acellular pertussis-hepatitis B-inactivated poliomyelitis-Haemophilus influenzae Type B Vaccine. Annals of the Academy of Medicine, Singapore 36:10, pages 801-896.
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Jane Zuckerman & Barbara Langer. (2005) Hepatitis B vaccination in a school age population: a feasibility study. Journal of Medical Virology 76:1, pages 47-54.
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