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Xenobiotica
the fate of foreign compounds in biological systems
Volume 30, 2000 - Issue 12
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Research Article

Determining the best animal model for human cytochrome P450 activities: a comparison of mouse, rat, rabbit, dog, micropig, monkey and man

J. J. P. Bogaards TNO Pharma, Department of Kinetics and Metabolism, PO Box 360, 3700 AJ Zeist, The Netherlands
,
M. Bertrand Technologie Servier, Rue du Eugene Vignat, Orleans, France
,
P. Jackson Servier Research and Development, Fulmer Hall, Fulmer, Slough SL3 6HH, UK
,
M. J. Oudshoorn TNO Pharma, Department of Kinetics and Metabolism, PO Box 360, 3700 AJ Zeist, The Netherlands
,
R. J. Weaver Technologie Servier, Rue du Eugene Vignat, Orleans, France
,
P. J. Van Bladeren Servier Research and Development, Fulmer Hall, Fulmer, Slough SL3 6HH, UK
&
B. Walther TNO Pharma, Department of Kinetics and Metabolism, PO Box 360, 3700 AJ Zeist, The Netherlands
 show all
Pages 1131-1152 | Published online: 22 Sep 2008

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